Results 51 to 60 of about 960 (152)

FIGURE 2 from Low Exposures to Amphibole or Serpentine Asbestos in Germline <i>Bap1</i>-mutant Mice Induce Mesothelioma Characterized by an Immunosuppressive Tumor Microenvironment

<p>TIME of crocidolite-induced MMs from <i>Bap1^+/−</i> mice. <b>A,</b> Serial sections of a crocidolite-induced MM from <i>Bap1-</i>mutant mouse stained with several different immune cell markers: CD3 (T cells; arrows); CD45R (B cells); F4/80 (macrophages; arrows); and NK1.1 (natural ...
Joseph R. Testa, Kathy Cai, Andres J. Klein-Szanto, Hatice U. Osmanbeyoglu, Parham Hadikhani, Mitchell Cheung, Maggie Ruan, Eleonora Sementino, Yuwaraj Kadariya   +8 more
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FIGURE 5 from Low Exposures to Amphibole or Serpentine Asbestos in Germline <i>Bap1</i>-mutant Mice Induce Mesothelioma Characterized by an Immunosuppressive Tumor Microenvironment

<p>IHC staining for CD39 (top; diffuse brown stain) and Ccr2 (bottom; punctate stain) in crocidolite-induced and chrysotile-induced MMs from <i>Bap1^+/−</i> mice. Arrows indicate examples of cells positively stained for Ccr2.</p>
Joseph R. Testa, Kathy Cai, Andres J. Klein-Szanto, Hatice U. Osmanbeyoglu, Parham Hadikhani, Mitchell Cheung, Maggie Ruan, Eleonora Sementino, Yuwaraj Kadariya   +8 more
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FIGURE 3 from Low Exposures to Amphibole or Serpentine Asbestos in Germline <i>Bap1</i>-mutant Mice Induce Mesothelioma Characterized by an Immunosuppressive Tumor Microenvironment

<p>Quantification of M2 macrophages in the TIME of asbestos-induced MMs from <i>Bap1^+/−</i> mice using an Aperio scanner, and IHC depicting arginase and iNOS staining of MM from asbestos-treated <i>Bap1^+/⁻</i> mice.
Joseph R. Testa, Kathy Cai, Andres J. Klein-Szanto, Hatice U. Osmanbeyoglu, Parham Hadikhani, Mitchell Cheung, Maggie Ruan, Eleonora Sementino, Yuwaraj Kadariya   +8 more
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FIGURE 1 from Low Exposures to Amphibole or Serpentine Asbestos in Germline <i>Bap1</i>-mutant Mice Induce Mesothelioma Characterized by an Immunosuppressive Tumor Microenvironment

<p>MM formation induced by crocidolite or chrysotile asbestos in mice with germline <i>Bap1</i> heterozygous mutation. MM formation induced by minimal exposure to crocidolite (<b>A</b> and <b>B</b>). <b>A,</b><i>Bap1^+/−</i> and <i>Bap1<sup>+/+</sup ...
Joseph R. Testa, Kathy Cai, Andres J. Klein-Szanto, Hatice U. Osmanbeyoglu, Parham Hadikhani, Mitchell Cheung, Maggie Ruan, Eleonora Sementino, Yuwaraj Kadariya   +8 more
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FIGURE 4 from Low Exposures to Amphibole or Serpentine Asbestos in Germline <i>Bap1</i>-mutant Mice Induce Mesothelioma Characterized by an Immunosuppressive Tumor Microenvironment

<p>Triple indirect IF of crocidolite- and chrysotile-induced MMs from <i>Bap1^+/−</i> mice. IF staining showing tumor cells as well as M1 and M2 macrophages in crocidolite- and chrysotile-induced MMs from 2 <i>Bap1^+/−</i> mice.
Joseph R. Testa, Kathy Cai, Andres J. Klein-Szanto, Hatice U. Osmanbeyoglu, Parham Hadikhani, Mitchell Cheung, Maggie Ruan, Eleonora Sementino, Yuwaraj Kadariya   +8 more
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FIGURE 7 from Low Exposures to Amphibole or Serpentine Asbestos in Germline <i>Bap1</i>-mutant Mice Induce Mesothelioma Characterized by an Immunosuppressive Tumor Microenvironment

<p>Preliminary clinical connections of mouse findings based on NCI human MM RNA-seq and germline mutation data (<a href="#bib16" target="_blank">16</a>). <b>A,</b> Comparison of <i>CCL2</i> mRNA expression levels based on <i>BAP1</i> germline mutation status in 100 MM samples from the NCI cohort ...
Joseph R. Testa, Kathy Cai, Andres J. Klein-Szanto, Hatice U. Osmanbeyoglu, Parham Hadikhani, Mitchell Cheung, Maggie Ruan, Eleonora Sementino, Yuwaraj Kadariya   +8 more
openaire   +1 more source

Supplementary Table S1 from Low Exposures to Amphibole or Serpentine Asbestos in Germline <i>Bap1</i>-mutant Mice Induce Mesothelioma Characterized by an Immunosuppressive Tumor Microenvironment

<p>Primary antibodies used for IHC, IF, and immunoblot analyses</p>
Joseph R. Testa, Kathy Cai, Andres J. Klein-Szanto, Hatice U. Osmanbeyoglu, Parham Hadikhani, Mitchell Cheung, Maggie Ruan, Eleonora Sementino, Yuwaraj Kadariya   +8 more
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Index-based FT-IR assessment of chrysotile detectability and environmental durability in asbestos cement materials. [PDF]

Sci Rep
Macher GZ, Beke D, Torma A.
europepmc   +1 more source

Hidden in plain sight: a narrative review on environmental exposures and the fight against mesothelioma. [PDF]

J Thorac Dis
Behinaein P, Patel JN, Okereke I.
europepmc   +1 more source

Fluorescent labeling of asbestos fiber for enhanced asbestos detection under fluorescence microscopy. [PDF]

Front Public Health
Kuroda A.
europepmc   +1 more source