Results 11 to 19 of about 19 (19)
COX‐2 in lung cancer: Mechanisms, development, and targeted therapies
Chronic Diseases and Translational Medicine, Volume 10, Issue 4, Page 281-292, December 2024.COX‐2 functions in the tumor microenvironment. Abstract Lung cancer (LC) is the leading cause of cancer‐related death worldwide, with non‐small cell lung cancer (NSCLC) comprising 85% of all cases. COX‐2, an enzyme induced significantly under stress conditions, catalyzes the conversion of free arachidonic acid into prostaglandins.
Xueqi Liu +4 more
wiley +1 more source
Respirology Case Reports, Volume 12, Issue 12, December 2024.Pulmonary vein thrombosis (PVT) is rarer than pulmonary artery thrombosis (PAT). The diagnosis of PVT is often difficult due to its nonspecific symptoms, such as cough, hemoptysis, and dyspnea, and can be missed if the clinician does not suspect it.
Yoshimasa Ogata +7 more
wiley +1 more source
Ergotamine Targets KIF5A to Facilitate Anoikis in Lung Adenocarcinoma
The Clinical Respiratory Journal, Volume 18, Issue 11, November 2024.Kinesin family member 5A (KIF5A) inhibits lung adenocarcinoma (LUAD) cell anoikis, while the small molecule drug Ergotamine targets and inhibits the expression of KIF5A, which in turn induces LUAD cell anoikis. ABSTRACT Background Kinesin family member 5A (KIF5A) has been reported to be closely related to cancer progression.
Bin Bao +3 more
wiley +1 more source
Risk of respiratory diseases among hospitalized patients with hidradenitis suppurativa
International Journal of Dermatology, Volume 63, Issue 11, Page 1528-1534, November 2024.Abstract Background Hidradenitis suppurativa (HS) is a systemic disorder associated with various metabolic and inflammatory comorbidities. Although HS shares risk factors and pathogenic pathways with various respiratory conditions, few studies have explored the relationship between HS and respiratory disease.
Nouf Almuhanna +3 more
wiley +1 more source
Health Science Reports, Volume 7, Issue 10, October 2024.Abstract Purpose Malignant Mesothelioma (MM) is a rare malignancy of the serosa membranes with a high mortality rate and long latent period. The relationship between a group of mineral fibers known as asbestos and mesothelioma is now well accepted in which people can be exposed to these fibers by various means during their lifetime and has been its ...
Alireza Rezvani +6 more
wiley +1 more source
Pulmonary fibrosis: pathogenesis and therapeutic strategies
MedComm, Volume 5, Issue 10, October 2024.This figure illustrates the interconnected and mutually reinforcing relationship between the study of mechanisms, diagnosis, and treatment of PF. The cycle begins with understanding the mechanisms underlying PF, which leads to the formulation of novel hypotheses. These hypotheses drive the development of new diagnostic tools and classification efforts,
Jianhai Wang +6 more
wiley +1 more source
Health Expectations, Volume 27, Issue 5, October 2024.ABSTRACT Introduction There is a pressing need to understand and explore the complex experiences and psychosocial support needs of people LWBC‐CM and their informal caregivers, to inform survivorship and supportive care interventions. Methods In‐depth qualitative interviews were conducted with people LWBC‐CM and their informal caregivers in Scotland ...
Debbie Cavers +4 more
wiley +1 more source
The health and economic burden of breathlessness, Australia, 2019: a national survey
Medical Journal of Australia, Volume 221, Issue 6, Page 324-332, September 2024.Abstract Objective To examine the impact of breathlessness on quality of life, health care use, productivity loss, and economic costs in Australia. Study design National internet‐based survey of Australian adults drawn from a web‐based survey panel (National Breathlessness Survey). Participants, setting Australian adults (18 years or older), nationally
Anthony P Sunjaya +6 more
wiley +1 more source
ACR Open Rheumatology, Volume 6, Issue 9, Page 568-580, September 2024.Objective Interstitial lung diseases (ILDs) are a heterogeneous group of disorders that can develop in patients with connective tissue diseases. Establishing autoimmunity in ILD impacts prognosis and treatment. Patients with ILD are screened for autoimmunity by measuring antinuclear autoantibodies, rheumatoid factors, and other nonspecific tests ...
Vaibhav Upadhyay +16 more
wiley +1 more source