Results 51 to 60 of about 352,893 (342)

Alleviation of Aging‐Related Hallmarks in a Mouse Model of Progeria via a Nanoparticle‐Based Artificial Transcription Factor

open access: yesAdvanced Functional Materials, EarlyView.
Oct4‐nanoscript, a biomimetic nanoparticle‐based artificial transcription factor, precisely regulates cellular rejuvenation by activating Oct4 target genes, restoring epigenetic marks, and reducing DNA damage. In a progeria model, it effectively rescued aging‐associated pathologies and extended lifespan.
Hongwon Kim   +8 more
wiley   +1 more source

Efficacy of endovascular repair in the treatment of retrograde ascending aortic intramural haematoma

open access: yesJournal of Cardiothoracic Surgery, 2023
Background The current treatment for retrograde ascending aortic intramural hematoma (RAIMH) remains challenging. This study aims to summarize the short-term results of endovascular repair in the treatment of retrograde ascending aortic intramural ...
Bailang Chen   +5 more
doaj   +1 more source

Spontaneous Laceration of Ascending Aorta [PDF]

open access: yesCirculation, 1973
Spontaneous laceration of the ascending aorta may result in (1) through-and-through laceration causing hemopericardium, (2) limited intramural dissection of blood (incomplete dissecting aneurysm), or (3) classical dissecting aneurysm. The latter is the most common manifestation.
Charles A. Murray, Jesse E. Edwards
openaire   +3 more sources

3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications: Possibilities and Limitations

open access: yesAdvanced Functional Materials, EarlyView.
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana   +2 more
wiley   +1 more source

Multiaxial pulsatile dynamics of the thoracic aorta and impact of thoracic endovascular repair

open access: yesEuropean Journal of Radiology Open, 2021
Purpose: The thoracic aorta is a highly mobile organ whose dynamics are altered by thoracic endovascular aorta repair (TEVAR). The aim of this study was to quantify cardiac pulsatility-induced multi-axial deformation of the thoracic aorta before and ...
Ga-Young Suh   +5 more
doaj  

Echinococcosis of the Heart and Ascending Aorta [PDF]

open access: yesCirculation, 2012
A 35-year-old woman with a history of disseminated thoracic echinococcosis treated by resection of an intraventricular septal cyst 11 years earlier in her country of origin presented for the first time to our cardiology outpatient clinic with atypical chest pain and shortness of breath.
Bernhard Gerber   +6 more
openaire   +2 more sources

Vorticity‐Facilitated Platelet Aggregation: a High Expansion‐Ratio Stenotic Microfluidic Platform Unravels the Role of Complex Flow Dynamics in Arterial Thrombosis

open access: yesAdvanced Healthcare Materials, EarlyView.
This study reveals how vorticity—a swirling flow pattern—enhances platelet aggregation and thrombus formation in high‐shear conditions. Using a custom microfluidic model, it is shows that vorticity promotes vWF–GPIbα interactions and calcium signaling, providing new insights into thrombosis mechanobiology and informing safer blood‐contacting medical ...
Jianfang Ren   +13 more
wiley   +1 more source

Fluid–structure interaction simulations outperform computational fluid dynamics in the description of thoracic aorta haemodynamics and in the differentiation of progressive dilation in Marfan syndrome patients [PDF]

open access: yesRoyal Society Open Science, 2020
Abnormal fluid dynamics at the ascending aorta may be at the origin of aortic aneurysms. This study was aimed at comparing the performance of computational fluid dynamics (CFD) and fluid–structure interaction (FSI) simulations against four-dimensional ...
R. Pons   +9 more
doaj   +1 more source

Acute aortitis of the ascending aorta [PDF]

open access: yesInteractive CardioVascular and Thoracic Surgery, 2017
We report a rare presentation of focal non-aneurysmal aortitis with mural thrombus of the ascending aorta. This was successfully treated with surgical resection and intravenous antibiotics. Pathology of the surgical specimen suggests that this was likely infectious aortitis, but the source of infection has not been identified.
Hartzell V. Schaff   +3 more
openaire   +3 more sources

Uniting 4D Printing and Melt Electrowriting for the Enhancement of Regenerative Small Diameter Vascular Grafts

open access: yesAdvanced Healthcare Materials, EarlyView.
A hybrid 4D printing strategy enables the fabrication of shape‐morphing, mechanically reinforced tubular constructs for vascular tissue engineering. By combining alginate‐methylcellulose hydrogels with melt electrowritten polycaprolactone fibers and protein‐based functionalization, this platform supports spatially organized co‐cultures of fibroblasts ...
Max von Witzleben   +8 more
wiley   +1 more source

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