Results 111 to 120 of about 3,196 (305)

Navigating adverse immunostimulation: A practical guide for clinical researchers

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Problem Setting As drug development moves towards more complex products, early clinical development programmes are increasingly hampered by unwanted and/or unexpected activation of the immune system (adverse immune stimulation, AIS). Solution At the Centre for Human Drug Research, we have introduced standardized procedures to make AIS manageable, while
Juliette A. van den Noort   +3 more
wiley   +1 more source

Malignant ascites

open access: yesJournal of British Surgery, 1996
Abstract Investigation and treatment of malignant ascites are often in the hands of the general surgeon and can be difficult. This article considers the aetiology and pathophysiology of malignant ascites and explores the best form of management.
Parsons, S. L.   +2 more
openaire   +3 more sources

Therapeutic drug monitoring of antimicrobials in a paediatric setting: A retrospective single‐centre study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Paediatric pharmacokinetics differ significantly from adults due to age‐related physiological changes, necessitating precise dose adjustments. However, data on therapeutic drug monitoring (TDM) implementation in paediatric setting remain limited.
Gianluca Gazzaniga   +20 more
wiley   +1 more source

PNEUMATOSE KYSTIQUE INTESTINALE REVELEE PAR UNE ASCITE

open access: yes, 2013
La pneumatose kystique intestinale est une affection rare et curieuse, définie par la présence de kystes gazeux dans la paroi digestive, d'évolution habituellement bénigne.
Mansouri, F.   +4 more
core  

Alterações da deglutição em pacientes com ascite: revisão sistemática / Alterations of deglutition in patient with ascites: systematic review

open access: yes, 2020
Objetivo: Apresentar evidências científicas com base em revisão sistemática da literatura (PRISMA) relacionando o possível impacto da disfagia em pacientes com ascite.
Aguiar, Bianca Rodrigues   +4 more
core  

Preditores de sobrevida com o fígado nativo em crianças com atresia biliar e ascite moderada ou grave [PDF]

open access: yes, 2014
Base teórica: A ascite é a complicação mais comum da cirrose, e seu surgimento representa sinal de mal prognóstico no curso da doença, sendo que 50% dos adultos cirróticos evoluem para o óbito em um período médio de 3,5 anos após seu primeiro episódio ...
Guedes, Renata Rostirola
core  

Impact of empiric potassium supplementation on mortality, sudden cardiac arrest and stroke in furosemide initiators

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim A prior non‐randomized study suggests that potassium supplementation may improve survival among furosemide initiators, and a randomized trial suggests that salt substitutes containing potassium might lower stroke risk. We conducted a retrospective cohort study using health‐care data to confirm or refute these associations among new users of ...
Thanh Phuong Pham Nguyen   +8 more
wiley   +1 more source

External validation of the BAN‐ADHF diuretic‐resistance score in the DAPA‐RESIST clinical trial

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Diuretic resistance in worsening heart failure (HF) is associated with poorer outcomes and, although common, can be challenging to identify. The recently developed BAN‐ADHF score can potentially identify patients with worsening HF at risk of diuretic resistance.
Dominic M. Alfonso   +10 more
wiley   +1 more source

Uma causa rara de hipertensão portal: Caso clínico A rare cause of portal hypertension: Case report

open access: yesAngiologia e Cirurgia Vascular, 2011
Apresenta-se caso clínico de doente com quadro de hipertensão portal pela presença de fístula artério-venosa entre a artéria gastroduodenal e a veia porta.
Joana Moreira   +10 more
doaj  

Ascite por helmintose e compactação gástrica em muar: relato de caso

open access: yes, 2022
Ascites in equids is rare, its occurrence may be related to physiological disorders, such as liver or kidney disorders, enteropathies, low protein diet and hydroelectrolytic imbalance.
Raphael, Ulisses Barbosa   +5 more
core  

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