Results 121 to 130 of about 182,211 (308)

Clinical implications of CT-detected ascites in gastric cancer: association with peritoneal metastasis and systemic inflammatory response

Insights into Imaging
Objectives This study aimed to evaluate the diagnostic significance of computed tomography (CT) detected ascites in gastric cancer (GC) with peritoneal metastasis (PM) and investigate its association with systemic inflammatory response.
Mengying Xu, Dan Liu, Le Wang, Shuangshuang Sun, Song Liu, Zhengyang Zhou   +5 more
doaj   +1 more source

Chromatin Binding of c-REL and p65 Is Not Limiting for Macrophage IL12B Transcription During Immediate Suppression by Ovarian Carcinoma Ascites

Frontiers in Immunology, 2018
Tumors frequently exploit homeostatic mechanisms that suppress expression of IL-12, a central mediator of inflammatory and anti-tumor responses. The p40 subunit of the IL-12 heterodimer, encoded by IL12B, is limiting for these functions.
Annika Unger, Florian Finkernagel, Nathalie Hoffmann, Felix Neuhaus, Barbara Joos, Andrea Nist, Thorsten Stiewe, Alexander Visekruna, Uwe Wagner, Silke Reinartz, Sabine Müller-Brüsselbach, Rolf Müller, Till Adhikary   +12 more
doaj   +1 more source

Antitumor and structure antioxidant activity relationship of Colchicine on Ehrlich ascites Carcinoma (EAC) in Female Mice [PDF]

, 2014
Colchicine has been reported to play important roles in hepatoprotection, anti-inflammation in vitro anti cancer activity. The present study was initiated to evaluate antioxidant and anti-cancer effects of colchicine (10µg/mice, i.p.) in mice after ...
Boshra, Sylvia A; Biochemistry Department, Faculty of Pharmacy, October 6 University, 6th October city, Egypt, Hussein, Mohammed Abdalla; prof. at Biochemistry Department, Faculty of Pharmacy, October 6 University, 6th October city, Egypt   +1 more
core   +2 more sources

PLIN2 Promotes Lipid Accumulation in Ascites‐Associated Macrophages and Ovarian Cancer Progression by HIF1α/SPP1 Signaling

Advanced Science
A major characteristic of ovarian cancer (OC) is its unique route of metastasis via ascites. The immune microenvironment in ascites remains understudied, leaving the mechanism of ascites‐mediated abdominal metastasis obscure.
Hui Luo, Xiaolu She, Yubo Zhang, Bingfan Xie, Shibo Zhang, Qianqian Li, Yangyang Zhou, Shuang Guo, Shushan Zhang, Yanhui Jiang, Yingying Dong, Jianzhong He, Lijie Wang, Qianqian Zhang, Yuan Zhuang, Panxia Deng, Feng Wang, Jihong Liu, Xin Chen, Huilong Nie, Huanhuan He   +20 more
doaj   +1 more source

Portal hypertension contributes to ascites formation via the Piezo1−nuclear factor kappa-B−aquaporin1 pathway in liver cirrhosis

Experimental and Molecular Medicine
Portal hypertension is critical to the development of ascites in liver cirrhosis. The aim of our study was to evaluate the contribution of portal hypertension to ascites formation and explore the underlying mechanism.
Ning Wei, Li Du, Zhuanglong Xiao, Lei Zhang, Yangyang Zhou, Haonan Gao, Minghui Liu, Chengbo Wang, Xiaohua Hou, Yan Li, Yuhu Song   +10 more
doaj   +1 more source

Editorial: quality of life and mortality in cirrhosis and ascites

, 2019
First paragraph: MacDonald et al1 report an important study showing that health‐related quality of life (HRQL) predicted mortality in 405 patients with cirrhosis and severe ascites. HRQL was assessed using the SF‐36 which has two main subscales assessing
Ronan O’Carroll, O’Carroll, Ronan
core   +1 more source

Examining the diagnostic process for ovarian cancer in Nova Scotia: A linked administrative data study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Ovarian cancer is the deadliest gynecological cancer in the developed world. The absence of screening for early detection of ovarian cancer and the non‐specific symptoms associated with the disease mean that timely diagnosis is difficult.
Chiara Gottheil, Christy Woolcott, Emily Gard Marshall, Katharina Kieser, Robin Urquhart   +4 more
wiley   +1 more source

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

iNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid, Weirong Fan, Farah Nazir, Yixiang Xing, Tengchuan Jin   +4 more
wiley   +1 more source

A novel method using the level of mobility to predict mortality in patients admitted for decompensated cirrhosis: A prospective study

, 2022
Liver Transplantation, EarlyView.
Andrew J. Groff, Marina Serper, Sunny Y. Tao, Pamela M. Bloomer, Michael A. Dunn, Andres Duarte‐Rojo   +5 more
wiley   +1 more source

Hepatic Encephalopathy and Age Were Assessed to Ameliorate the Underestimation of the Model for End‐Stage Liver Disease Score in Patients With Acute‐on‐Chronic Liver Failure

iNew Medicine, EarlyView.
This study demonstrates that the model for end‐stage liver disease (MELD) score significantly underestimates 90‐day mortality in acute‐on‐chronic liver failure (ACLF) patients (AUC: 0.556) compared to non‐ACLF patients (area under the receiver operating characteristic curve [AUC]: 0.848).
Guanghou Chen, Qifei Guan, Yufeng Gao, Zhenhua Zhang, Hongchuan Zhao, Beicheng Sun   +5 more
wiley   +1 more source