Results 191 to 200 of about 167,102 (249)

Lithospermic Acid Improves Doxorubicin‐Induced Cardiomyopathy Through Sirtuin‐3‐Mediated Deacetylation of p53

open access: yesPhytotherapy Research, EarlyView.
Lithospermic acid (LA) inactivates the p53 signaling pathway via directly targeting SIRT3, thereby alleviating oxidative stress and abnormal apoptosis in the progression of doxorubicin (Dox)‐induced cardiomyocytes. ABSTRACT Doxorubicin (Dox)‐induced cardiomyopathy (DIC) is characterized by significant myocardial damage that can progress to dilated ...
Yining Zhao   +13 more
wiley   +1 more source

Cell Culture Substrate Variation Alters Extracellular Vesicle Biogenesis Without Affecting Non‐Coding Repeat RNA Profile

open access: yesSmall, EarlyView.
Cell culture biomechanical conditions influence extracellular vesicles (EVs) production in patient‐derived pancreatic adenocarcinoma (PDAC) cell lines. When grown in 3D conformation and in hydrogels with lower elasticity (0.5kPA), PDAC cells produce higher numbers of EVs, compared with cells grown in 2D on classic cell culture plastic.
Sara I. Veiga   +9 more
wiley   +1 more source

Selective Wettability–Driven Evaporation‐Enhanced Redox Cycling for Robust and Ultrasensitive Detection of Viral Particles

open access: yesSmall Methods, EarlyView.
ABSTRACT Timely detection of viral infections, particularly in settings outside centralized laboratories, is essential for controlling outbrakes. Small electrochemical biosensors are appealing because they are fast, require microliter sample volumes, and can be integrated into portable devices.
Pouya Soltan Khamsi   +3 more
wiley   +1 more source

Comparison of ultrasound with computed tomography and whole‐body diffusion‐weighted MRI in prediction of surgical outcome using ESMO‐ESGO criteria in patients with tubo‐ovarian carcinoma: prospective ISAAC study

open access: yesUltrasound in Obstetrics &Gynecology, EarlyView.
ABSTRACT Objective To test the non‐inferiority of extended abdominopelvic ultrasound examination compared with contrast‐enhanced computed tomography (CT) and whole‐body diffusion‐weighted magnetic resonance imaging (WB‐DWI/MRI) in discriminating preoperatively between resectable and non‐resectable disease based on the European Society for Medical ...
D. Fischerova   +26 more
wiley   +1 more source

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