Results 81 to 90 of about 65,503 (309)
Advanced Healthcare Materials, EarlyView.The image shows a schematic form a nanobody‐conjugated theranostic prodrug (NBD) platform targeting tumor‐associated αvβ3 integrin. The NBD system integrates selective nanobody‐mediated tumor recognition, glutathione‐responsive disulfide cleavage for doxorubicin release, and aza‐BODIPY‐based near‐infrared fluorescence for real‐time imaging.
Sanu Karan +13 more
wiley +1 more source
Ascorbic acid deficiency and the flavin-containing monooxygenase [PDF]
Biochemical Pharmacology, 1986 Activity of the flavin-containing monooxygenase (FMO) was reduced significantly in ascorbic acid deficient guinea pigs. Reduction in oxidation of dimethylaniline (DMA) and of thiobenzamide was associated with a decrease in the activity of the FMO. In both ascorbate supplemented and deficient guinea pig hepatic 12,000 g supernatant fractions, SKF-525A ...
Brodfuehrer, Joanne I. +1 more
openaire +3 more sources
Bioengineered 3D hPSC‐Cholangiocyte Ducts With Physiological Signals for Biliary Disease Modeling
Advanced Healthcare Materials, EarlyView.Tian and colleagues generated a bioengineered bile duct from human pluripotent stem cell (hPSC)‐derived intrahepatic cholangiocytes within a high‐throughput, 384‐well platform to systematically examine the influence of biliary physiological signals including fluid flow, stromal cells and bile acids, and models intrahepatic biliary disease progression ...
Britney Tian +10 more
wiley +1 more source
ASCORBIC ACID STATUS IN DIFFERENT POPULATION CATEGORIES DURING THE RUSSIAN-UKRAINIAN WAR
Проблеми екології та медициниOur study aimed to examine the ascorbic acid (AA) status of the Ukrainian population during wartime conditions. Ascorbic acid is one of the most essential vitamins in human nutrition.
N.D. Gerasymenko +5 more
doaj +1 more source
An Unexpected Case of Scurvy in a Peritoneal Dialysis Patient
Case Reports in Nephrology and Dialysis, 2017 This case describes an obese adult male peritoneal dialysis patient who presented with a pruritic follicular rash. Nutrient deficiency was not suspected initially in this case because there was no history of protein-calorie malnutrition, but the patient ...
Raymonda El Khoury +3 more
doaj +1 more source
Development and validation of chromatographic methods to study folate derivatives produced by yeasts [PDF]
, 2007 Folate, or folic acid, is an important water soluble B vitamin that exists in many different forms. Its presence is necessary for synthesis of DNA and RNA and methylation of homocysteine to methionine.
Patring, Johan
core
Oxidative stress in the pathogenesis of systemic scleroderma: An overview [PDF]
, 2018 Systemic sclerosis (SSc) is a rare disorder of the connective tissue characterized by fibrosis of the skin, skeletal muscles and visceral organs. Additional manifestations include activation of the immune system and vascular injury. SSc causes disability
Gambardella, Lucrezia +5 more
core +1 more source
Advanced Healthcare Materials, EarlyView.This study presents the first entirely isogenic heart‐on‐chip, unifying cardiomyocytes, fibroblasts, and endothelial cells from a single iPSC source. The platform reveals a critical biological insight: the endothelium actively shields cardiac tissue from drug‐induced toxicity, challenging the predictive accuracy of conventional, avascular models for ...
Karine Tadevosyan +12 more
wiley +1 more source
Reduction of a-tocopherylquinone Model Compound With Various Reductant [PDF]
, 2001 In order to study the possibility of tranformation of a-tocopherylquinone (TQ) into a more oxidiseable compound and also to find out the recycling effect in the cells, an experiment was conducted by reducing the model compound 2-(3- hydroxy-3-methylbutyl)
Kohar, Indrajati
core
Does taking vitamin, mineral and fatty acid supplements prevent cognitive decline? A systematic review of randomized controlled trials [PDF]
, 2008 Background Observational studies have shown associations between nutritional status and cognition in later life but evidence from intervention studies is unclear.
Avenell, Alison, Jia, X, McNeill, G
core +1 more source