Results 171 to 180 of about 430,600 (318)

Mechanisms of SCN2A loss of function do not predict presence or phenotype of epilepsy

Epilepsia, EarlyView.
Abstract Objective SCN2A loss‐of‐function (LoF) variants are associated with epilepsy (onset age ≥ 3 months), intellectual disability (ID), and autism spectrum disorder (ASD). Despite numerous identified variants and the description of phenotypic subgroups, relationships between Nav1.2 channel dysfunction and clinical phenotypes remain unclear.
Marsha Tan, Beatrice Southby Goad, Meagan Allen, Jill Rodda, Kay L. Richards, Simone L. Ardern‐Holmes, Daniel Bamborschke, Daniel Fritzen, Inna Hughes, Kate Riney, Ana Roche Martinez, Angelo Russo, Adriane Sinclair, Stefano Sartori, Marina Trivisano, Angela De Dominicis, Nicola Specchio, Rikke S. Møller, Ingrid E. Scheffer, Walid Fazeli, Markus Wolff, Steven Petrou, Katherine B. Howell, Géza Berecki   +23 more
wiley   +1 more source

Wybrane aspekty pojmowania czasu przez osoby z ASD

Logopaedica Lodziensia
Celem artykułu jest ukazanie wybranych aspektów pojmowania kategorii czasu przez osoby w spektrum autyzmu. Specyfika przetwarzania i percypowania czasu przez te osoby została ukazana na tle uwarunkowań neurobiologicznych i kulturowych.
Marta Korendo, Ewa Zmuda
doaj   +1 more source

asd v1

, 2015

openaire   +1 more source

Characterizing early behavioral and social–emotional problems in young children with SCN1A+ Dravet syndrome: Findings from the ENVISION prospective natural history study

Epilepsia, EarlyView.
Abstract Objective Dravet syndrome (DS) is the prototypic developmental and epileptic encephalopathy, characterized by drug‐resistant seizures, developmental slowing, and many other morbidities. Detailed characterization of behavioral phenotypes and social–emotional skill development are limited.
Ingrid E. Scheffer, M. Scott Perry, Joseph Sullivan, Susana Boronat, James Wheless, Andreas Brunklaus, Linda Laux, Anup D. Patel, Colin Roberts, Dennis Dlugos, Deborah Holder, Kelly Knupp, Matt Lallas, Steven Phillips, Eric Segal, Dennis Lal, Elaine Wirrell, Sameer M. Zuberi, Rebecca Shaffer, Mary Wojnaroski, Madison M. Berl, Sarah Christensen, Emma S. James, Maria Candida Vila, Norman Huang, Jacqueline S. Gofshteyn, Salvador Rico   +26 more
wiley   +1 more source

Frontiers in EEG as a tool for the management of pediatric epilepsy: Past, present, and future

Epilepsia Open, EarlyView.
Abstract Electroencephalography (EEG) has evolved into an indispensable tool in pediatric epilepsy, fundamentally transforming the diagnosis, classification, and management of this condition. This review chronicles the historical journey of EEG from its groundbreaking inception to its current pivotal role in delineating distinct pediatric epilepsy ...
Hiroki Nariai
wiley   +1 more source

Neuropsychological profile and social cognition in children and adolescents with temporal lobe epilepsy

Epilepsia Open, EarlyView.
Abstract Objective To characterize the neuropsychological profile and social cognition, particularly Theory of Mind (ToM), in 45 children and adolescents with temporal lobe epilepsy (TLE) compared with 56 age, gender, and schooling‐matched healthy controls.
Claudia Accolla, Martina Preti, Pietro Cappelletto, Salvatore De Masi, Carmen Barba, Renzo Guerrini   +5 more
wiley   +1 more source

From Brain Health to Brain Economy

Brain Health, EarlyView.
Yongjun Wang
wiley   +1 more source

Plant‐derived extracellular vesicle‐like particles as novel osteoanabolic agents: Activating bone morphogenetic protein 2/Smads signaling axis for bone regeneration in postmenopausal osteoporosis

Interdisciplinary Medicine, EarlyView.
Illustration depicting the isolation of Dipsaci Radix derived extracellular vesicle‐like particles and their function in alleviating osteoporosis. (A) Extraction and characterization detection process of extracellular vesicle‐like particles derived from Dipsaci Radix roots. (B) Cell experiments in vitro, Dipsaci Radix derived extracellular vesicle‐like
Qing Zhao, Yue Cao, Zhengting Wu, Yingqi Cao, Qi You, Yuanyuan Xia, Xuejun Tan, Dongxiao Li, Tianxin Qiu, Xiuping Cai, Zhaodi Guo, Lei Zheng, Kewei Zhao   +12 more
wiley   +1 more source

Systematic review: Safety and efficacy of atomoxetine in children and adolescents with autism spectrum disorder

JCPP Advances, EarlyView.
This systematic review aimed to assess the current evidence on the efficacy and safety of Atomoxetine in common clinical symptoms of autism spectrum disorder (ASD) for children and adolescents. With limited studies available, there is a need for more high‐power studies for the use of Atomoxetine in children and adolescents with autism spectrum disorder.
Nihit Gupta, Daniel Boyes, Hunter Hanlon‐Taylor, Mayank Gupta   +3 more
wiley   +1 more source

Targeting intolerance of uncertainty in young children diagnosed with autism: A randomized controlled trial of a parent‐mediated group intervention

JCPP Advances, EarlyView.
In this clinical trial, parents of young children between four and 7 years of age, diagnosed with autism and experiencing anxiety related to uncertainty, completed an 8 week group program. Post‐group, parents reported significant reductions in the impact of uncertainty‐related anxiety on their child and family, with effects also noted on parenting ...
Claudia S. Y. Ong, Jacqui Rodgers, Matthew N. Cooper, Zac Dempsey, Rebecca Eaton, Katia Haines, Rebecca Kuzminski, Iliana Magiati, Murray T. Maybery, Mirko Uljarević, John Wray, Andrew J. O. Whitehouse, Gail A. Alvares   +12 more
wiley   +1 more source