Results 171 to 180 of about 208,814 (273)

The role of rare copy number variants in early‐onset depression

open access: yesJCPP Advances, EarlyView.
Abstract Background Depression is a highly heterogeneous condition. Depression with an onset in childhood and early adolescence has a worse clinical course, is more heritable, and shows a lower genetic correlation with other depression subtypes, than does later‐onset depression.
Charlotte A. Dennison   +12 more
wiley   +1 more source

Isolating transdiagnostic effects reveals specific genetic profiles in psychiatric disorders

open access: yesJCPP Advances, EarlyView.
Abstract Background Evidence indicates substantial genetic overlap between psychiatric diagnoses. Accounting for these transdiagnostic effects can sharpen research on disorder‐specific genetic architecture and patterns of comorbidity. Methods We applied genomic structural equation modeling to genome‐wide association study summary statistics from 11 ...
Engin Keser   +6 more
wiley   +1 more source

Common cause versus dynamic mutualism: Insights into ADHD's common comorbidities

open access: yesJCPP Advances, EarlyView.
Abstract Background Contemporary classification systems differ in their conceptualization of ADHD as either an externalizing or neurodevelopmental condition, with both perspectives promoting the common cause model as an explanation of ADHD's comorbidity.
Zheyue Peng, Ashley L. Watts
wiley   +1 more source

Reliability, validity, and change over time in disinhibited and disruptive behaviors assessed with the age‐adapted disruptive behavior diagnostic observation schedule in children aged 5–12 years with ADHD

open access: yesJCPP Advances, EarlyView.
Abstract Background Previous research has shown that the disruptive behavior diagnostic observation schedule (DB‐DOS) is a valid and reliable clinic‐based assessment of disinhibited and disruptive behaviors in preschoolers. We adapted the DB‐DOS for use in children aged 5–12 years, examined its psychometric properties, and evaluated its ability to ...
Margreet Bierens   +6 more
wiley   +1 more source

Body weight in autism spectrum disorder: A systematic review and meta‐analysis

open access: yesJCPP Advances, EarlyView.
Abstract Background Evidence on the relationship of autism spectrum disorder (ASD) to overweight/obesity and underweight is mixed. Moreover, it is unclear how this relationship changes with age. Methods We carried out a systematic review (SR) with meta‐analysis on the association between ASD and obesity, overweight and underweight across the life span.
Victoria Nieuwenhuys‐Ruiz   +8 more
wiley   +1 more source

Computational mechanisms of perception in autism revealed using games inspired by rodent operant tasks. [PDF]

open access: yesSci Adv
Chakravarty S   +6 more
europepmc   +1 more source

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