The role of rare copy number variants in early‐onset depression
Abstract Background Depression is a highly heterogeneous condition. Depression with an onset in childhood and early adolescence has a worse clinical course, is more heritable, and shows a lower genetic correlation with other depression subtypes, than does later‐onset depression.
Charlotte A. Dennison +12 more
wiley +1 more source
Overlapping and distinct intrinsic connectivity of hippocampal and triple networks in autistic individuals with and without a comorbid condition of ADHD. [PDF]
Chen L, Riggs A, Luckenbach N.
europepmc +1 more source
Isolating transdiagnostic effects reveals specific genetic profiles in psychiatric disorders
Abstract Background Evidence indicates substantial genetic overlap between psychiatric diagnoses. Accounting for these transdiagnostic effects can sharpen research on disorder‐specific genetic architecture and patterns of comorbidity. Methods We applied genomic structural equation modeling to genome‐wide association study summary statistics from 11 ...
Engin Keser +6 more
wiley +1 more source
Cunermuspir, a Copper(I)-Niacin Complex, Modulates Mitochondrial Respiration and Cellular Oxidant Handling in Fibroblasts from Children with Autism Spectrum Disorder. [PDF]
Wallace S, Lawes S, Scheck AC, Frye RE.
europepmc +1 more source
Common cause versus dynamic mutualism: Insights into ADHD's common comorbidities
Abstract Background Contemporary classification systems differ in their conceptualization of ADHD as either an externalizing or neurodevelopmental condition, with both perspectives promoting the common cause model as an explanation of ADHD's comorbidity.
Zheyue Peng, Ashley L. Watts
wiley +1 more source
Factors Associated With Professionals' Context-Specific Trust in AI-Based Screening for Autism Spectrum Disorder: Cross-Sectional Survey Study. [PDF]
Ohmoto Y +3 more
europepmc +1 more source
Abstract Background Previous research has shown that the disruptive behavior diagnostic observation schedule (DB‐DOS) is a valid and reliable clinic‐based assessment of disinhibited and disruptive behaviors in preschoolers. We adapted the DB‐DOS for use in children aged 5–12 years, examined its psychometric properties, and evaluated its ability to ...
Margreet Bierens +6 more
wiley +1 more source
Structural language profiles in children with autism spectrum disorder and developmental language disorder: a systematic review. [PDF]
Doghadze I, Gagoshidze T.
europepmc +1 more source
Body weight in autism spectrum disorder: A systematic review and meta‐analysis
Abstract Background Evidence on the relationship of autism spectrum disorder (ASD) to overweight/obesity and underweight is mixed. Moreover, it is unclear how this relationship changes with age. Methods We carried out a systematic review (SR) with meta‐analysis on the association between ASD and obesity, overweight and underweight across the life span.
Victoria Nieuwenhuys‐Ruiz +8 more
wiley +1 more source
Computational mechanisms of perception in autism revealed using games inspired by rodent operant tasks. [PDF]
Chakravarty S +6 more
europepmc +1 more source

