Results 11 to 20 of about 430,600 (318)

Detection of autism spectrum disorder (ASD) in children and adults using machine learning

Scientific Reports, 2023
Autism spectrum disorder (ASD) presents a neurological and developmental disorder that has an impact on the social and cognitive skills of children causing repetitive behaviours, restricted interests, communication problems and difficulty in social ...
M. Farooq, R. Tehseen, Maidah Sabir, Zabihullah Atal   +3 more
semanticscholar   +1 more source

Broad transcriptomic dysregulation occurs across the cerebral cortex in ASD

Nature, 2022
Neuropsychiatric disorders classically lack defining brain pathologies, but recent work has demonstrated dysregulation at the molecular level, characterized by transcriptomic and epigenetic alterations1–3.
Michael Jeffrey Gandal, J. Haney, B. Wamsley, C. Yap, Sepideh Parhami, Prashant S. Emani, Nathan Chang, George T. Chen, Gil D. Hoftman, Diego de Alba, Gokul Ramaswami, C. Hartl, A. Bhattacharya, C. Luo, Ting Jin, Daifeng Wang, R. Kawaguchi, Diana Quintero, J. Ou, Y. E. Wu, N. Parikshak, V. Swarup, T. G. Belgard, M. Gerstein, B. Pasaniuc, D. Geschwind   +25 more
semanticscholar   +1 more source

ASD and ADHD Comorbidity: What Are We Talking About?

Frontiers in Psychiatry, 2022
According to the scientific literature, 50 to 70% of individuals with autism spectrum disorder (ASD) also present with comorbid attention deficit hyperactivity disorder (ADHD).
Camille Hours, C. Recasens, J. Baleyte
semanticscholar   +1 more source

Innate immune dysfunction and neuroinflammation in autism spectrum disorder (ASD)

Brain, behavior, and immunity, 2022
Autism spectrum disorder (ASD) is a highly heterogeneous neurodevelopmental disorder characterized by communication and social behavior deficits.
H. Hughes, R.J.Moreno, P. Ashwood
semanticscholar   +1 more source

Brief Report: Impact of COVID-19 on Individuals with ASD and Their Caregivers: A Perspective from the SPARK Cohort

Journal of Autism and Developmental Disorders, 2021
The impact of the 2019 coronavirus pandemic (COVID-19) in the United States is unprecedented, with unknown implications for the autism community. We surveyed 3502 parents/caregivers of individuals with an autism spectrum disorder (ASD) enrolled in Simons
L. C. White, J. K. Law, A. Daniels, J. Toroney, Brianna M. Vernoia, Sabrina Xiao, P. Feliciano, W. Chung, The Spark Consortium   +8 more
semanticscholar   +1 more source

ASD-SAENet: A Sparse Autoencoder, and Deep-Neural Network Model for Detecting Autism Spectrum Disorder (ASD) Using fMRI Data

Frontiers in Computational Neuroscience, 2021
Autism spectrum disorder (ASD) is a heterogenous neurodevelopmental disorder which is characterized by impaired communication, and limited social interactions.
Fahad Almuqhim, F. Saeed
semanticscholar   +1 more source

ASD-DiagNet: A Hybrid Learning Approach for Detection of Autism Spectrum Disorder Using fMRI Data [PDF]

Front. Neuroinform., 2019
Heterogeneous mental disorders such as Autism Spectrum Disorder (ASD) are notoriously difficult to diagnose, especially in children. The current psychiatric diagnostic process is based purely on the behavioral observation of symptomology (DSM-5/ICD-10 ...
Taban Eslami, Vahid Mirjalili, A. Fong, A. Laird, F. Saeed   +4 more
semanticscholar   +1 more source

Autism and mild epilepsy associated with a de novo missense pathogenic variant in the GTPase effector domain of DNM1

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView., 2023
Abstract Dynamin 1 is a GTPase protein involved in synaptic vesicle fission, which facilitates the exocytosis of neurotransmitters necessary for normal signaling. Pathogenic variants in the DNM1 gene are associated with intractable epilepsy, often manifested as infantile spasms at onset, developmental delay, and a movement disorder, and are located in ...
Davide Mei, Elena Parrini, Claudia Bianchini, Maria Luisa Ricci, Renzo Guerrini   +4 more
wiley   +1 more source

Structural and Pragmatic Language Impairments in Children Evaluated for Autism Spectrum Disorder (ASD)

Journal of Autism and Developmental Disorders, 2021
Pragmatic language impairments are common in neurodevelopmental disorders, especially in autism spectrum disorder (ASD). The relationship between structural language skills and pragmatic competence in children with autistic symptoms, however, is largely ...
Lise Reindal, T. Nærland, B. Weidle, S. Lydersen, O. Andreassen, A. Sund   +5 more
semanticscholar   +1 more source

Is Motor Impairment in Autism Spectrum Disorder (ASD) Distinct From Developmental Coordination Disorder (DCD)? A Report From the SPARK Study.

Physical Therapy, 2020
BACKGROUND Motor impairments are pervasive in Autism Spectrum Disorder (ASD) however, children with ASD rarely receive a dual diagnosis of Developmental Coordination Disorder (DCD).
A. Bhat
semanticscholar   +1 more source