Results 171 to 180 of about 10,703 (258)

Early Postoperative Adverse Events (≤ 30 Days) in Spinal Oncology: Defining the Incidence, Severity, and Predictors in a Mixed Prospective Cohort Including Intradural and Metastatic Spinal Tumors

International Journal of Cancer, EarlyView.
ABSTRACT Complication reporting in spinal tumor surgery remains inconsistently defined. We aimed to quantify the incidence, severity, and spectrum of early (≤ 30 days) postoperative adverse events (AEs) in spinal tumor surgery and to identify predictors of overall and serious complications using standardized severity grading.
Meltem Ivren, Philip Dao Trong, Maximilian Klass, Martin Dugas, Sebastian Ille, Sandro M. Krieg, Pavlina Lenga   +6 more
wiley   +1 more source

Postoperative Complications Following LSCS: Incidence, Risk Factors, and Management-A Prospective Observational Study from the Bundelkhand Region. [PDF]

J Pharm Bioallied Sci
Patel P, Banga SK, Jain S, Khare P, Bhatnagar S, Patel S, Patel P.   +6 more
europepmc   +1 more source

Unlocking insights: Validating a comprehensive model for predicting spontaneous preterm delivery and microbial invasion in women facing preterm labor

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Preterm labor is a multifactorial syndrome with diverse etiologies such as infection, inflammation, uteroplacental dysfunction, stress, and immune dysregulation. Identifying women at high risk remains a challenge, and multivariate prediction models have been developed to enhance risk stratification.
Ester del Barco, Nerea Maiz, Clara Franco‐Jarava, Mireia Vargas, Silvia Arévalo, María A. Sánchez‐Durán, Carlota Rodó, Manel Mendoza, Marta Dalmau, Alba Casellas, Manuel Hernández‐González, Anna Suy, María Goya   +12 more
wiley   +1 more source

Decision-ready evidence for vital pulp therapy: a network meta-analysis of bioactive materials in mature permanent teeth. [PDF]

Front Dent Med
Elmsmari F, Abdelsayed RB, Albasoumi Q, Aljafarawi T, Patro S, Pawar AM.   +5 more
europepmc   +1 more source

All‐Trans Retinoic Acid Promotes Endometrial Regeneration and Angiogenesis Associated With Wnt/β‐Catenin Signaling in a Mouse Model of Intrauterine Adhesion

iNew Medicine, EarlyView.
ATRA promotes endometrial regeneration, angiogenesis, and uterine receptivity in intrauterine adhesion, at least in part through activation of Wnt/β‐catenin signaling. ABSTRACT Objective To investigate the therapeutic effects of all‐trans retinoic acid (ATRA) on endometrial repair and the underlying mechanisms.
Ting Luo, Ting Liao, Yunxia Cao, Zhaolian Wei   +3 more
wiley   +1 more source

Turkish neonatal nurses' knowledge regarding the enteral feeding in preterm infants: a descriptive, cross-sectional study. [PDF]

BMC Nurs
Gözen D, Aykanat Gi̇rgi̇n B, Çarikçi F, Temi̇zsoy E.   +3 more
europepmc   +1 more source

Sel1l preserves condylar cartilage matrix homeostasis by regulating PERK signaling

Interdisciplinary Medicine, EarlyView.
Our study revealed that the expression of Sel1l was downregulated in OA cartilage and that Sel1l deficiency induced cartilage catabolism. Mechanistically, Sel1l depletion aberrantly activated PERK signaling and resulted in ER stress. PERK inhibition rescued the phenotype of Sel1l‐deficient chondrocytes and alleviated TMJOA pathogenesis.
Xinqi Huang, Zinan Cen, Zhihe Zhao, Xiao Cen   +3 more
wiley   +1 more source

Management of Persistent Postoperative Cerebrospinal Fluid Leak Following Removal of Lumbar Spinal Drain After Thoracoabdominal Aortic Aneurysm Repair. [PDF]

Ann Card Anaesth
Suvetha S, Babu S, Raman SP, Dash PK.
europepmc   +1 more source

Targeting eIF5A combats breast cancer progression by ClpP‐dependent mitochondrial oxidative stress

Interdisciplinary Medicine, EarlyView.
This study identified the eIF5A‐ClpP axis as a key driver of breast cancer progression. Targeting eIF5A suppresses tumor growth by inducing ClpP‐dependent mitochondrial oxidative stress, revealing a novel therapeutic vulnerability. Abstract Breast cancer (BC) poses a persistent global health challenge, necessitating new therapeutic targets.
Jinmei Zhu, Baoyuan Tang, Bei Xie, Haohua Deng, Haitang Yang, Lei Ma, Ziqing Zhang, Yicheng Ma, Xingyuan Ma, Shuaiyang Wang, Jing Li, Lei Zhao, Wengui Shi, Linjing Li   +13 more
wiley   +1 more source

Metrnβ drives sepsis immunosuppression via macrophage reprogramming: A novel prognostic biomarker and therapeutic target

Interdisciplinary Medicine, EarlyView.
Metrnβ serves as a novel prognostic biomarker for sepsis and that targeted blockade of the Metrnβ‐c‐Kit axis represents a promising therapeutic strategy for sepsis. Abstract Sepsis is a heterogeneous syndrome critically driven by immunosuppression, yet lacking personalized prognostic markers and therapeutic targets. Here, we provide evidence to support
Xiao Li, Ai Chen, Chen Zhang, Meihong Da, Yonghui Liu, Zhi He, Chenyan Yuan, Shuo Ma, Yuming Yao, Dawen Chen, Meiling Zhou, Zhixin Song, Wenjing Lu, Chun‐Kwok Wong, Guoqiu Wu, Xun Gao   +15 more
wiley   +1 more source