Results 151 to 160 of about 690,322 (292)

Peptide‐Enabled Nanoplatforms for Malaria and Leishmaniasis: From Intracellular Targeting to Translational Diagnostic Perspectives

open access: yesChemMedChem, Volume 21, Issue 18, 28 September 2026.
Peptide‐enabled nanoplatforms offer multifunctional strategies for the treatment and diagnosis of malaria and leishmaniasis. Liposomal, polymeric, and metallic nanocarriers, together with cell‐penetrating peptides and parasite‐derived mimotopes, can improve targeted drug delivery, stability, bioavailability, and intracellular localization.
Christian S. Carnero Canales   +7 more
wiley   +1 more source

N8‐Modified Quino[4,3,2‐Kl]acridines as Promising Antimalarial G‐Quadruplex Ligands

open access: yesChemBioChem, Volume 27, Issue 17, 14 September 2026.
A series of extended aromatic compounds with tunable substituents was synthesized using a multistep methodology which allows various substitutions of the 8H‐quino[4,3,2‐kl]acridine scaffold. This chemical series appeared as a promising way to new antimalarial drug candidates with high activity (IC50 < 100 nM), exhibiting a novel mechanism of action ...
Steve Saulnier   +10 more
wiley   +1 more source

Single‐Cell and Spatial Transcriptomics Unveil Key Regulators Governing Cell Differentiation for Schistosoma japonicum Sexual Development

open access: yesAdvanced Science, Volume 13, Issue 53, 24 September 2026.
Using single‐cell and spatial transcriptomics, we identified key regulators that govern cell differentiation involved in parasite development and egg laying in Schistosoma japonicum. This comprehensive study establishes a foundational resource for understanding schistosome biology, deciphers the regulatory programs underlying cell differentiation and ...
Zhigang Lu   +9 more
wiley   +1 more source

Patterns of asexual reproduction of the soybean aphid, Aphis glycines (Matsumura), with and without the secondary symbionts Wolbachia and Arsenophonus, on susceptible and resistant soybean genotypes. [PDF]

open access: yesFront Microbiol, 2023
Giordano R   +10 more
europepmc   +1 more source

Island Invader: Rugulopteryx okamurae and the Challenge for Macaronesian Coasts

open access: yesAquatic Conservation: Marine and Freshwater Ecosystems, Volume 36, Issue 9, September 2026.
ABSTRACT Since 2015, Rugulopteryx okamurae, a brown seaweed native to the Northwest Pacific, has become one of the most conspicuous marine invaders in the European continental coastal waters. Its recent establishment in the Macaronesian archipelagos (the Azores, Madeira and Canary Islands) has produced significant ecological changes, including ...
Rodrigo Riera   +4 more
wiley   +1 more source

Contrasting Temporal Dynamics of Ostracod (Crustacea) Communities in Protected and Impacted Areas in a Brazilian Floodplain

open access: yesAquatic Conservation: Marine and Freshwater Ecosystems, Volume 36, Issue 9, September 2026.
ABSTRACT Environmental integrity is vital for the long‐term preservation of freshwater biodiversity, which is currently among the most threatened on Earth due to anthropogenic pressures such as dam construction. The present study investigated the temporal responses of ostracod communities over 8 years (2017–2024) in the Upper Paraná River floodplain ...
Jhony Kenji Nakata   +3 more
wiley   +1 more source

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