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ASFV complete genomes sequences alignment
2020ASFV complete genomes sequences ...
Aslanyan Levon +2 more
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ZBP1-mediated macrophage necroptosis inhibits ASFV replication
2023AbstractAfrican swine fever (ASF) is an infectious disease characterized by hemorrhagic fever, highly pathogenic, and severe mortality in domestic pigs caused by the African swine fever virus (ASFV). ASFV is a large DNA virus and primarily infects porcine monocyte macrophages.
Keshan Zhang +21 more
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Quantification of ASFV DNA and RNA in Ornithodoros Soft Ticks
2022Molecular biology methods are highly sensitive to detect the genome of pathogens and to study their biology. Polymerase chain reaction (PCR) and reverse transcription followed by a polymerase chain reaction (RT-PCR) permit the detection of the presence and the replication of African swine fever virus in soft ticks.
Pereira de Oliveira, Rémi +2 more
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ASFV p30 interacts with CCAR2 and MATR3 to promote ASFV replication
Veterinary MicrobiologyAfrican swine fever (ASF) is a highly contagious and lethal disease caused by the African swine fever virus (ASFV). Currently, effective vaccines are not available for the prevention and control of ASF. ASFV is susceptible to mutations as it has a large genome and encodes numerous proteins. In addition to evading the host immune response, ASFV utilizes
Xuefei, Chu +10 more
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ASFV subunit vaccines: Strategies and prospects for future development
Microbial PathogenesisAfrican Swine Fever (ASF) is an acute, highly contagious, and lethal disease caused by the African Swine Fever Virus (ASFV), posing a severe threat to the global pig farming industry. Although live vaccines are currently available, preventing and controlling ASF remains a considerable challenge.
Yuchen Zhang +6 more
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Porcine immune responses to African swine fever virus (ASFV) infection
Veterinary Immunology and Immunopathology, 1994Immune responses mediating protection against ASFV are poorly understood. Anti-ASFV antibodies may influence the course of the clinical disease but they have never been found to neutralize the virus. Recent developments on cellular defense mechanisms, using swine protection models, and on the induction and role of some cytokines warrant further ...
C L, Martins, A C, Leitão
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Characterization of ASFV Proteins
1987The analysis of polypeptides made in cells infected with African swine fever virus (ASFV) by high-resolution polyacrylamide gel electrophoresis revealed the synthesis of at least 44 polypeptides ranging in molecular weight from 9.5 K to 243 K. Most of the proteins are synthesized within the first eight hours after infection and can be classified as ...
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Deoxycholic acid inhibits ASFV replication by inhibiting MAPK signaling pathway
International Journal of Biological MacromoleculesAfrican swine fever (ASF) is an acute, febrile, highly contagious infection of pigs caused by the African swine fever virus (ASFV). The purpose of this study is to understand the molecular mechanism of ASFV infection and evaluate the effect of DCA on MAPK pathway, so as to provide scientific basis for the development of new antiviral drugs.
Qi, Gao +8 more
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