Results 91 to 100 of about 112,547 (248)

Efficacy and Safety of Nanoencapsulated Sirolimus Plus Pegadricase: Results From the Randomized, Placebo‐Controlled Phase 3 Trials

open access: yesArthritis &Rheumatology, EarlyView.
Objective DISSOLVE I and II examined the efficacy and safety of nanoencapsulated sirolimus (NAS) plus pegadricase (NASP) in patients with uncontrolled gout (UG). Methods In these double‐blind, placebo‐controlled Phase 3 trials of NASP, patients were randomized 1:1:1 to infusions of high‐dose (HD) or low‐dose (LD) NAS plus pegadricase (HD NASP, LD NASP,
Herbert S. B. Baraf   +15 more
wiley   +1 more source

Serum levels of interleukin-33 and mesencephalic astrocyte derived neurotrophic factors in patients with major depressive disorder: a cross-sectional comparative design

open access: yesBMC Psychiatry
Background Major depressive disorder (MDD) is a debilitating health condition that has significant morbidity and mortality rates. Depression can be caused due to social, biological, environmental, psychological, and genetic factors.
Zabun Nahar   +6 more
doaj   +1 more source

Pharmacokinetics, effectiveness and safety of certolizumab pegol in children and adolescents with active juvenile idiopathic arthritis: 9+‐year results from a multicenter, open‐label study

open access: yesArthritis &Rheumatology, Accepted Article.
Objective To assess the pharmacokinetics, effectiveness, safety, and immunogenicity of certolizumab pegol (CZP) in polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods Pediatric Arthritis Study of Certolizumab Pegol (NCT01550003), a multicenter, open‐label study, enrolled patients 2–17 years with active pcJIA and inadequate response ...
Hermine I Brunner   +28 more
wiley   +1 more source

Tax Incentives and Firms’ Decision on Innovation and Export: Case from Chinese Listed Advanced Manufacturers

open access: yesEconomies
This study applies the bivariate probit model to a panel of Chinese listed advanced manufacturers to investigate the relationship between tax incentives and firms’ decision on export and R&D.
Sangho Kim, Zhe Li
doaj   +1 more source

Deucravacitinib in Active Psoriatic Arthritis: Efficacy and Safety up to 52 Weeks From the Randomized, Double‐Blind, Phase 3 POETYK PsA‐2 Trial

open access: yesArthritis &Rheumatology, Accepted Article.
Objective To assess the efficacy and safety of deucravacitinib, an oral, selective tyrosine kinase 2 inhibitor, in patients with psoriatic arthritis (PsA) who were naive to biologic disease‐modifying antirheumatic drugs or received tumor necrosis factor inhibitors. Methods In the 52‐week (W), double‐blind, placebo‐controlled, phase 3 POETYK PsA‐2 study
Philip J. Mease   +20 more
wiley   +1 more source

ChatGPT as a learning scaffold in critical theory education among Bangladeshi students

open access: yesDiscover Education
This paper examines how undergraduate students in Bangladesh have used generative AI, particularly ChatGPT, as an informal learning tool to address the linguistic and conceptual challenges of critical theory. Using interviews, written reflections, and AI
Keya Chakraborty   +2 more
doaj   +1 more source

“Hands‐On” white matter anatomy: Using Air Anatomy gestures and tractography on simple brain sections to enhance teaching of white matter directions

open access: yesAnatomical Sciences Education, EarlyView.
Abstract Teaching white matter (WM) anatomy to undergraduates is challenging. This is partly because WM fibers are oriented intricately and Klingler's dissection, the gold standard method used to demonstrate it, often requires time, advanced anatomical knowledge, and refined dissection skills.
Doris George Yohannan   +7 more
wiley   +1 more source

Dissection versus prosection by anatomical region: Evaluating a regional group dissection curriculum in medical education

open access: yesAnatomical Sciences Education, EarlyView.
Abstract Gross anatomy education has undergone significant changes due to evolving curricular demands, leading to reduced hands‐on dissection opportunities in many medical schools. The purpose of this study was to compare the academic performance of medical student dissectors and those assigned to prosection‐based learning across anatomical regions ...
Andrew J. Gaetano   +5 more
wiley   +1 more source

A survey on the teaching of introductory nervous system content in undergraduate courses

open access: yesAnatomical Sciences Education, EarlyView.
Abstract Teaching introductory or foundation level concepts about anatomy and physiology of the nervous system to undergraduate students presents a conundrum for educators—how to provide students with sufficient knowledge for a successful learning experience and outcome without overwhelming students and impacting student progression and retention.
Gabrielle Todd   +2 more
wiley   +1 more source

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