Results 131 to 140 of about 3,166,912 (294)

Efficacy and Safety of Nanoencapsulated Sirolimus Plus Pegadricase: Results From the Randomized, Placebo‐Controlled Phase 3 Trials

Arthritis &Rheumatology, EarlyView.
Objective DISSOLVE I and II examined the efficacy and safety of nanoencapsulated sirolimus (NAS) plus pegadricase (NASP) in patients with uncontrolled gout (UG). Methods In these double‐blind, placebo‐controlled Phase 3 trials of NASP, patients were randomized 1:1:1 to infusions of high‐dose (HD) or low‐dose (LD) NAS plus pegadricase (HD NASP, LD NASP,
Herbert S. B. Baraf, Puja P. Khanna, Milan Petronijevic, Mamuka Lortkipanidze, Anand Patel, Kwabena Ayesu, Michael H. Pillinger, Atul Singhal, Joanna Sobierska, Jacquie Christie, Peter Traber, Rehan Azeem, Wesley DeHaan, Hugues Santin‐Janin, Bhavisha Desai, Alan Kivitz   +15 more
wiley   +1 more source

Association of catechol-o-methyltransferase (COMT) gene rs4680 polymorphism and risk of obsessive-compulsive disorder in a clinically characterized Bangladeshi cohort

Beni-Suef University Journal of Basic and Applied Sciences
Background The catechol-O-methyltransferase (COMT) gene is crucial for breaking down dopamine. The Val158Met polymorphism (rs4680) affects its enzymatic activity. Our study aims to assess the association of the rs4680 (Val158Met) polymorphism in the COMT
Ahmad Niaz Rahman, Marline Gomes, M. M. A. Shalahuddin Qusar, Mohammad Shahriar, Mohiuddin Ahmed Bhuiyan, Md. Rabiul Islam, Zabun Nahar   +6 more
doaj   +1 more source

Pharmacokinetics, Effectiveness and Safety of Certolizumab Pegol in Children and Adolescents With Active Juvenile Idiopathic Arthritis: 9+‐Year Results From a Multicenter, Open‐Label Study

Arthritis &Rheumatology, EarlyView.
Objective The purpose of this study was to assess the pharmacokinetics, effectiveness, safety, and immunogenicity of certolizumab pegol (CZP) in polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods Pediatric Arthritis Study of Certolizumab Pegol (NCT01550003), a multicenter, open‐label study, enrolled patients aged 2 to 17 years with ...
Hermine I. Brunner, Lyudmila Grebenkina, Irina Nikishina, Ekaterina Alexeeva, Vyacheslav Chasnyk, Carlos Abud‐Mendoza, Nadina Rubio‐Pérez, Heinrike Schmeling, María del Rocio Maldonado‐Velázquez, Diane Brown, Andrew Zeft, Esi Morgan, C. Egla Rabinovich, Daniel Kingsbury, Hulya Bukulmez, Beth Gottlieb, Thomas Griffin, Lisa Imundo, Stacey Tarvin, Earl Silverman, Laura Shaughnessy, Saori Shimizu, Paulette Williams, Rocío Lledó‐García, Gauri Utturkar, Baran Ufuktepe, Alberto Martini, Daniel J. Lovell, Nicolino Ruperto, the Paediatric Rheumatology International Trials Organisation (PRINTO); the Pediatric Rheumatology Collaborative Study Group (PRCSG), Hermine I. Brunner, Lyudmila Grebenkina, Irina Nikishina, Ekaterina Alexeeva, Vyacheslav Chasnyk, Carlos Abud‐Mendoza, Nadina Rubio‐Pérez, Heinrike Schmeling, María del Rocio Maldonado‐Velázquez, Diane Brown, Andrew Zeft, Esi Morgan, C. Egla Rabinovich, Daniel Kingsbury, Hulya Bukulmez, Beth Gottlieb, Thomas Griffin, Lisa Imundo, Stacey Tarvin, Earl Silverman, Alberto Martini, Daniel L. Lovell, Nicolino Ruperto   +52 more
wiley   +1 more source

Supersymmetric spectrum for vector multiplet on Euclidean AdS2

Journal of High Energy Physics
Quantum study of supersymmetric theories on Euclidean two dimensional anti-de Sitter space (EAdS2) requires complexified spectrum. For a chiral multiplet, we showed that the spectrum of the Dirac operator acquires a universal shift of i/2 from the real ...
Alfredo González Lezcano, Imtak Jeon, Augniva Ray   +2 more
doaj   +1 more source

Asia Pacific Center for Military Law : annual report 2014

, 2014
Asia Pacific Center for Military Law (APCML) A collaboration between Melbourne Law School (University of Melbourne) & Defence Legal (Department of ...
Asia-Pacific Center for Military Law
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REVIEW: Global networks and news beyond Utopia: Review of Information Technologies for Newspaper Publishing in the Asia-Pacific, edited by Belinda Hopkinson

, 1997
Review of Information Technologies for Newspaper Publishing in the Asia-Pacific, edited by Belinda Hopkinson. Paris: UNESCO. Today, as more people become interested in what is happening outside their village, province and South Pacific nation, more and ...
Robie, David
core   +1 more source

Deucravacitinib in Active Psoriatic Arthritis: Efficacy and Safety Up to 52 Weeks From the Randomized, Double‐Blind, Phase 3 POETYK PsA‐2 Trial

Arthritis &Rheumatology, EarlyView.
Objective To assess the efficacy and safety of deucravacitinib, an oral, selective tyrosine kinase 2 inhibitor, in patients with psoriatic arthritis (PsA) who were naive to biologic disease‐modifying antirheumatic drugs or received tumor necrosis factor inhibitors. Methods In the 52‐week, double‐blind, placebo‐controlled, phase 3 Program for Evaluation
Philip J. Mease, Vinod Chandran, April W. Armstrong, Ricardo Blanco, Alexis Ogdie, Evan L. Siegel, Alice B. Gottlieb, Xiaofeng Zeng, Diamant Thaçi, Mitsumasa Kishimoto, Hendrik Schulze‐Koops, Alan Kivitz, Eva Dokoupilová, Akimichi Morita, Eric M. Ruderman, Michael Plewinski, Kejia Wang, Caroline Sardinas, Eleni Vritzali, John Vaile, Atul Deodhar   +20 more
wiley   +1 more source

“Hands‐On” white matter anatomy: Using Air Anatomy gestures and tractography on simple brain sections to enhance teaching of white matter directions

Anatomical Sciences Education, EarlyView.
Abstract Teaching white matter (WM) anatomy to undergraduates is challenging. This is partly because WM fibers are oriented intricately and Klingler's dissection, the gold standard method used to demonstrate it, often requires time, advanced anatomical knowledge, and refined dissection skills.
Doris George Yohannan, Rohini Punja, Thomas Iype, Chandrasekharan Kesavadas, Bejoy Thomas, Kannanvilakom Govindapillai Umesan, Aswathy Maria Oommen, Usha Devi Keezhathil Bhargavi   +7 more
wiley   +1 more source

Dissection versus prosection by anatomical region: Evaluating a regional group dissection curriculum in medical education

Anatomical Sciences Education, EarlyView.
Abstract Gross anatomy education has undergone significant changes due to evolving curricular demands, leading to reduced hands‐on dissection opportunities in many medical schools. The purpose of this study was to compare the academic performance of medical student dissectors and those assigned to prosection‐based learning across anatomical regions ...
Andrew J. Gaetano, Jason Howard, Luke Ritter, Maha Khan, Nicolas Jozefowski, Eva L. Murdoch   +5 more
wiley   +1 more source

Towards effective regional security architecture for the Asia Pacific [PDF]

, 2014
The proliferation of multilateral security processes and institutions in the Asia Pacific in the wake of the Cold War is a testament to the region\u27s constructive and collegial spirit toward addressing security challenges.

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