Results 201 to 210 of about 4,699,148 (388)

Integrated Transcriptome and Metabolomics Analyses Show MYC as a Potential Therapeutic Target for Behçet's Uveitis

open access: yesAdvanced Science, EarlyView.
Integrated single‐cell transcriptomic and metabolomic analyses reveal that MYC‐driven glycolysis activates the PI3K‐AKT‐FOXO1 pathway, disrupting Th17/Treg balance and promoting uveitis. MYC inhibition restores immune homeostasis and alleviates disease symptoms.
He Li   +11 more
wiley   +1 more source

Asian Trade Structures and Trade Potential : An Initial Analysis of South and East Asian Trade [PDF]

open access: yes
A frontier of potential trade is constructed for trade flows from a world trade matrix of trade determinants to compare East Asian trade performance with that of South Asia.
Kaliappa Kalirajan   +2 more
core   +1 more source

Advanced Pharmaceutical Nanotechnologies Applied for Chinese Herbal Medicines

open access: yesAdvanced Science, EarlyView.
This review offers a comprehensive overview of pharmaceutical nanotechnology strategies to address limitations associated with the complex material basis and relative mild therapeutic efficacy of Chinese herbal medicines, and summarizes the advantages of these strategies.
Jiameng Li   +11 more
wiley   +1 more source

Trans-in-Asia, Asia-in-Trans [PDF]

open access: yesTSQ: Transgender Studies Quarterly, 2018
Helen Hok-Sze Leung   +2 more
openaire   +2 more sources

Interference Pattern Caused by Bilateral Bone Conduction Stimulation Impairs Sound Localization

open access: yesAdvanced Science, EarlyView.
This work explores how crosstalk‐induced wave interference affects bone conduction (BC) sound localization. Using a theoretical model, cadaveric vibrometry, and psychoacoustic tests, atypical BC lateralization patterns are revealed that contradict air conduction (AC) principles.
Liu‐Jie Ren   +7 more
wiley   +1 more source

Identifying Myeloid‐Derived Suppressor Cells and Lipocalin‐2 as Therapeutic Targets for Intervertebral Disc Degeneration

open access: yesAdvanced Science, EarlyView.
Inflammatory dysregulation drives intervertebral disc degeneration via stage‐dependent immune cellular dynamics. Single‐cell transcriptomics and genetic risk mapping revealed a shift from LCN2high myeloid‐derived suppressor cells maintaining disc repair in early stages to IL1B+ macrophage‐dominated pathology in advanced disease.
Changmeng Zhang   +6 more
wiley   +1 more source

Health-Related Quality of Life Assessment in Prostate Cancer Patient Undergoing Androgen Deprivation Therapy: Real-World Experience in the READT Study

open access: yesThe World Journal of Men's Health
Purpose: To investigate the effect of androgen deprivation therapy (ADT) on health-related quality of life (HRQOL) in Asian men with all stages of prostate cancer.
Jasmine Lim   +14 more
doaj   +1 more source

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