Results 241 to 250 of about 2,084,399 (362)

Alternative Models for Anticancer Drug Discovery From Natural Products Using Binary Tumor‐Microenvironment‐on‐a‐Chip

open access: yesAdvanced Science, EarlyView.
This study presents a binary tumor‐microenvironment‐on‐a‐chip (T‐MOC) system incorporating multicellular tumor spheroids (MCTs) as an alternative preclinical platform to evaluate the efficacy of anticancer natural products. The T‐MOC model reproduces in vivo drug delivery barriers and physiological conditions, enabling morphological analysis to predict
Youngwon Kim   +7 more
wiley   +1 more source

Diabetes in Asia and the Pacific: Implications for the Global Epidemic

open access: yesDiabetes Care, 2016
A. Nanditha   +7 more
semanticscholar   +1 more source

SNORA58 Facilitates Radioresistance via Suppressing JNK1‐Mediated Ferroptosis in Esophageal Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
In ESCC patients, SNORA58 exhibits heterogeneous expression patterns. Its aberrant overexpression stabilizes CTCF by inhibiting ubiquitin‐mediated degradation, leading to the attenuation of JNK1‐mediated ferroptosis induced by radiotherapy through disruption of intracellular iron homeostasis, and ultimately contributes to radioresistance ...
Yinli Zheng   +14 more
wiley   +1 more source

Artificial Intelligence Is Stereotypically Linked More with Socially Dominant Groups in Natural Language

open access: yesAdvanced Science, EarlyView.
AI is not seen through an unbiased lens. People tend to stereotype AI as competent and link it with socially advantaged groups—such as men, the wealthy, the young, and prestigious occupations—raising concerns that such perceptions may deepen existing social divides rather than bridge them.
Zixi Wang   +4 more
wiley   +1 more source

Quantification of regional variation in ultra-processed food consumption and its sociodemographic correlates across Bangladesh, India, Pakistan, and Sri Lanka: insights from the South Asia Biobank. [PDF]

open access: yesLancet Reg Health Southeast Asia
Bhagtani D   +19 more
europepmc   +1 more source

Comparative Single‐Cell Transcriptomic Landscape Reveals the Regulatory Mechanisms of Lactation during Selective Breeding in Asian Water Buffalo

open access: yesAdvanced Science, EarlyView.
In this study, a comprehensive single‐cell transcriptome atlas of river and swamp buffalo, encompassing 12 tissues and 397,011 cells, is constructed. Differential expression analyses identify metabolic and secretory tissues and cell types that mediate the divergence of milk production.
Dongmei Dai   +13 more
wiley   +1 more source

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