Results 41 to 50 of about 2,084,399 (362)

Green Innovation and Finance in Asia

Asian Economic Policy Review, 2020
Green innovation and green finance are two key components of sustainable development. In the most populous, fastest growing region in the world, Asian countries are pressed to maintain economic growth while addressing climate change and environmental ...
Clarence Tolliver, Clarence Tolliver, Hidemichi Fujii, A. Keeley, A. Keeley, Shunsuke Managi   +5 more
semanticscholar   +1 more source

Deadly heat waves projected in the densely populated agricultural regions of South Asia

Science Advances, 2017
Climate change poses a deadly heat wave risk to South Asia due to population density, poverty, and outdoor working conditions. The risk associated with any climate change impact reflects intensity of natural hazard and level of human vulnerability ...
E. Im, J. Pal, E. Eltahir
semanticscholar   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Whole-genome sequencing of 128 camels across Asia reveals origin and migration of domestic Bactrian camels

Communications Biology, 2020
The domestic Bactrian camels were treated as one of the principal means of locomotion between the eastern and western cultures in history. However, whether they originated from East Asia or Central Asia remains elusive.
Liang Ming, Liyun Yuan, L. Yi, Guohui Ding, Guohui Ding, S. Hasi, Gangliang Chen, Tuyatsetseg Jambl, Nemat Hedayat-Evright, Mijiddorj Batmunkh, Garyaeva Khongr Badmaevna, T. Gan-Erdene, Batsukh Ts, Wenbin Zhang, Azhati Zulipikaer, Hosblig, Erdemt, A. Natyrov, Prmanshayev Mamay, Narenbatu, G. Meng, C. Narangerel, Orgodol Khongorzul, Jing He, Le Hai, Weili Lin, Sirendalai, Sarentuya, Aiyisi, Yixue Li, Zhen Wang, Jirimutu   +31 more
semanticscholar   +1 more source

Evaluation of KRAS and NRAS mutations in metastatic colorectal cancer: an 8‐year study of 10 754 patients in Turkey

Molecular Oncology, EarlyView.
This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci, Izzet Akiva, Yavuz Hakan Ozon, Hakan Berkil, Huseyin Karadayi, Omer Dizdar, Suayib Yalcin   +6 more
wiley   +1 more source

Safety and Efficacy of Everolimus Plus Exemestane in Postmenopausal Women with Treatment-refractory Hormone Receptor-positive, Human Epidermal Growth Factor Receptor 2-negative Advanced Breast Cancer: Analysis from EVEREXES Taiwan Subset

Journal of Cancer Research and Practice, 2023
Background: This phase IIIb, open-label study enrolled patients from nine Asian and Middle Eastern countries to evaluate the safety and efficacy of the combination therapy in underrepresented patient populations from the Breast Cancer Trials of Oral ...
Yuan-Ching Chang, Kun-Ming Rau, Dar-Ren Chen, Tsu-Yi Chao, Ming-Feng Hou, Chiun-Sheng Huang*   +5 more
doaj   +1 more source

Raphin‐1 mediates the survival and sensitivity to radiation of pediatric‐type diffuse high‐grade glioma via phosphorylated eukaryotic initiation factor 2α‐dependent and ‐independent processes

Molecular Oncology, EarlyView.
Raphin‐1 reduces the survival of PED‐DHGG cells and enhances their radiation sensitivity through both PeIF2α‐dependent and PeIF2α‐independent mechanisms. Raphin‐1 sustains elevated levels of PeIF2α, contributing to its PeIF2α‐dependent effects. Additionally, raphin‐1 interacts with CReP to mediate a separate radiosensitizing pathway that operates ...
Karin Eytan, Moshe Leitner, Amos Toren, Shoshana Paglin, Michal Yalon   +4 more
wiley   +1 more source

A Tale of Amalgamation of Three Permo-Triassic Collage Systems in Central Asia: Oroclines, Sutures, and Terminal Accretion

, 2015
The Central Asian Orogenic Belt records the accretion and convergence of three collage systems that were finally rotated into two major oroclines. The Mongolia collage system was a long, N–S-oriented composite ribbon that was rotated to its current ...
W. Xiao, B. Windley, S. Sun, Jiliang Li, Baochun Huang, Chunming Han, C. Yuan, Minjia Sun, Hanlin Chen   +8 more
semanticscholar   +1 more source

The GenomeAsia 100K Project enables genetic discoveries across Asia

Nature, 2019
The underrepresentation of non-Europeans in human genetic studies so far has limited the diversity of individuals in genomic datasets and led to reduced medical relevance for a large proportion of the world’s population.
Jeffrey D. Eric W. Aakrosh Hie Lim Changhoon Ravi Kushal E Wall Stawiski Ratan Kim Kim Gupta Suryamohan Gusar, J. Wall, E. Stawiski, A. Ratan, Hie-Lim Kim, Changhoon Kim, Ravi Gupta, Kushal Suryamohan, Elena S. Gusareva, Rikky W. Purbojati, T. Bhangale, V. Stepanov, V. Kharkov, Markus S. Schröder, V. Ramprasad, J. Tom, S. Durinck, Qixin Bei, Jiani Li, Joseph Guillory, Sameer Phalke, A. Basu, Jeremy Stinson, S. Nair, S. Malaichamy, N. Biswas, J. Chambers, K. Cheng, J. T. George, Seik-Soon Khor, Jong-Il Kim, B. Cho, R. Menon, Thiramsetti Sattibabu, A. Bassi, Manjari Deshmukh, A. Verma, Vivek Gopalan, Jong-Yeon Shin, Mahesh Pratapneni, S. Santhosh, K. Tokunaga, B. M. Md-Zain, Kok-Gan Chan, M. Parani, Purushothaman Natarajan, M. Hauser, R. Allingham, C. Santiago-Turla, Arkasubhra Ghosh, S. G. Gadde, C. Fuchsberger, L. Forer, S. Schoenherr, H. Sudoyo, J. Lansing, Jonathan Scott Friedlaender, G. Koki, M. Cox, M. Hammer, T. Karafet, K. C. Ang, S. Mehdi, V. Radha, V. Mohan, P. Majumder, S. Seshagiri, Jeong-Sun Seo, S. Schuster, A. Peterson   +69 more
semanticscholar   +1 more source