Results 101 to 110 of about 106,783 (260)

A Rare De Novo Missense Mutation in IFT122 Confers a Genetic Susceptibility Factor of Idiopathic Pediatric Uveitis Via Trio‐based Whole‐Exome Sequencing

Advanced Science, EarlyView.
A rare de novo IFT122‐A773E variant is identified in idiopathic pediatric uveitis and shown to exacerbate retinal inflammation and barrier dysfunction. Mechanistically, the variant enhances IFT43 interaction, elevates calcium signaling, and activates the MEK/ERK/FRA1 axis, revealing a previously unrecognized cilia‐associated pathway that may increase ...
Qian Zhou, Jiaxing Huang, Yilin Wang, Xingran Li, Xianyang Liu, Lingyu Dai, Hongshun Li, Qingfeng Wang, Jiangyi Liu, Guannan Su, Wanyun Zhang, Yang Deng, Qingfeng Cao, Yujie Lai, Xiang Luo, Changwei Huang, Ling Chen, Shengping Hou, Peizeng Yang   +18 more
wiley   +1 more source

Eski Çağ Kappadokia'sında Beyaz Syrialılar Leukosyrioi Kavramı

Selçuk Üniversitesi Sosyal Bilimler Enstitüsü Dergisi, 2020
Eski Çağ’da Kappadokia Bölgesi; coğrafi konumu, sahip olduğu imkânlar ve geniş yüz ölçümüyle tarihin tüm devirleri boyunca çeşitli insan toplulukları için iskân yeri ve değişik siyasi teşekküllerin ellerinde tutmayı arzuladıkları bir bölge olmuştur ...
Şenol Yurdakul
doaj  

Optimized Cas9‐Enriched Nanopore Sequencing and Analysis Workflow for Clinical Diagnosis of Repeat Expansion Disorders

Advanced Science, EarlyView.
An optimized Cas9‐enriched nanopore sequencing workflow, combined with STRiker, enables simultaneous analysis of disease‐associated STR loci from patient blood. The nCATS–STRiker workflow detects repeat expansions, de novo repeat motifs, interruption patterns, and methylation in a single assay, improving the genetic diagnosis of previously undiagnosed ...
Seungbok Lee, Chanju Jung, Minjeong Kim, Narae Kim, Gue‐Ho Hwang, Soon‐Tae Lee, Kon Chu, Sang Kun Lee, Han‐Joon Kim, Jong‐Hee Chae, Sangsu Bae, Jangsup Moon   +11 more
wiley   +1 more source

Global Burden and Temporal Trends of Early‐Onset Tracheal, Bronchial, and Lung Cancer: An Analysis of GLOBOCAN 2022 and GBD 2023 Data

Advanced Science, EarlyView.
This study systematically assessed the global burden and temporal trends of EOTBL cancer in individuals aged 15–49 years. Smoking, ambient particulate matter pollution, and secondhand smoke remain dominant risk factors. Countries within the same Human Development Index (HDI) category exhibit distinct epidemiological trajectories, underscoring the need ...
Ye Tian, Weihao Zhang, Yao Lu, Bruce F. O'Hara, Jingjing Hu, Hanqi Feng, Jing Di, Lei Zhang, Xueying Yang   +8 more
wiley   +1 more source

Mausoleums of the Eastern Regions of the Golden Horde

Золотоордынское обозрение
The purpose of the study: To consider the composition of architecture in the eastern regions of the Golden Horde, using the example of monuments of memorial architecture.
Zilivinskaya E.D.
doaj   +1 more source

Cranial variability and differentiation among golden jackals (Canis aureus) in Europe, Asia Minor and Africa. [PDF]

Zookeys, 2020
Stoyanov S.
europepmc   +1 more source

Transposable Element Dynamics Drive the Genomic Evolution and Phenotypic Diversification of Allotetraploid Common Carp

Advanced Science, EarlyView.
By integrating 516 whole‐genome resequencing datasets and 236 transcriptomes of allotetraploid common carp, this study establishes the first population‐scale atlas of transposable element (TE) variation in teleost species. TE bursts, relaxed purifying selection, and lineage‐specific loss of ancient insertions shape genome evolution and phenotypic ...
Shuimu Hu, Zhou Jiang, Lin Chen, Gowena Ling Yi Goh, Weijing Li, Qian He, Xintong Chen, Rui Li, Yuxuan Liu, Ning Li, Tao Zhou, Peng Xu   +11 more
wiley   +1 more source

Earrings from Nicaea in Bithynia (south-eastern Marmara)

Cercetări Arheologice
In this brief paper 34 earrings are presented, all of which are curated in the Archaeological Museum of İznik in south-western Marmara region of Turkey. They are significant, as very few items of jewellery from Bithynia have been published.
Fatih Hakan Kaya, Musa Albayrak, Martin Henig, Ergün Lafli   +3 more
doaj   +1 more source

A Facial Foundation Model for Clinical Biomarker Prediction and Real‐World Mobile Deployment

Advanced Science, EarlyView.
MedicalFaceFound is a facial foundation model developed through three‐stage progressive pre‐training, adapting representations from general vision to facial structure and clinical phenotypes. Using a single facial image, it estimates 62 biomarkers across multiple physiological systems and supports downstream risk prediction for cardiovascular ...
Tingfeng Xu, Huixuan Xu, Li Lin, Fei Wang, Yaodong Ding, Shuangqiao Liao, Xingyu Chen, Jichen Wen, Hongqiang Zhao, Jing Hao, Weixiang Zhao, Gong Zhang, Shiguang Shan, Yong Zeng, Hu Han, Minxian Wang   +15 more
wiley   +1 more source

On Horseback through Asia Minor

, 1996
Frederick Burnaby (1842–85) joined the Royal Horse Guards in 1859, but, when not assigned to active duty, he crafted his own adventures. He ballooned across the English Channel, and travelled in Spain, Asia Minor and Russia. He was wounded, and eventually killed, fighting for the British Empire.
openaire   +2 more sources