Results 41 to 50 of about 17,378,334 (354)

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Perceived discrimination and coping with substance use among Asian Americans during the COVID-19 pandemic: a cross-sectional analysis

BMC Public Health
Background Race/ethnicity-related discrimination against Asian Americans increased during the COVID-19 pandemic. Previous studies have found an association between discrimination and use of alcohol and other drugs (AOD) as a form of coping. In this study,
Adrian Matias Bacong, Dale Dagar Maglalang, Janice Y. Tsoh, Anne Saw   +3 more
doaj   +1 more source

Asian American Crossroads Lecture Series: Manu Karuka

, 2019
This flyer promotes Manu Karuka's lecture over his book Empire's Tracks: Indigenous Nations, Chinese Workers, and the Transcontinental Railroad.
Center for Asian American Studies
core   +1 more source

De novo synthesis of short‐chain aldehydes and hydrocarbons secreted by the brown marmorated stink bug Halyomorpha halys

FEBS Open Bio, EarlyView.
The brown marmorated stink bug, Halyomorpha halys, mainly secretes 4‐oxo‐(E)‐2‐hexenal, (E)‐2‐decenal, dodecane and tridecane, a mixture representative of that released by many heteropterans. We demonstrated that H. halys can synthesise these secretory components de novo using dietary glucose.
Haruna Fujimori, Koji Noge
wiley   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

Time and Change in Advaita—Gauḍapāda in Dialogue with Vasiṣṭha and Nāgārjuna

Religions
In the classical philosophical landscape of India, the Advaita of Śaṅkara occupies central stage. Besides the Upaniṣadic literature, the Gauḍapāda-kārikā (GK) of Gauḍapāda is the primary text in this school.
Sthaneshwar Timalsina
doaj   +1 more source

Mission-Centered Engagement with Asian American Student Veterans

Journal of Veterans Studies, 2019
This article draws qualitatively on the experiences, reflections, and expressions of Asian American student veterans through Asian American Studies courses and activities the authors have led in the decade between 2006 and 2016, at an urban public ...
Peter Nien-chu Kiang, Shirley Suet-ling Tang, Matthew M. Seto   +2 more
doaj   +1 more source

When “model minorities” become “yellow peril”—Othering and the racialization of Asian Americans in the COVID‐19 pandemic

Sociology Compass, 2021
Using the ongoing coronavirus disease 2019 (COVID‐19) pandemic as a case study, this paper engages with debates on the assimilation of Asian Americans into the US mainstream.
Yao Li, Harvey L. Nicholson
semanticscholar   +1 more source