Results 181 to 190 of about 344,668 (257)

The Effect of Online Parent Training With and Without Coaching Support on the Well‐Being of Families of Children With Neurodisabilities: A Randomized Controlled Trial

Autism Research, EarlyView.
ABSTRACT Families of children with neurodisabilities often face significant child behavioral challenges that can affect overall family functioning and well‐being. This randomized controlled trial (RCT) used family resilience theory as the investigative framework to examine the impact of an online parenting program designed to address child behavioral ...
Jeffrey McCrossin, Ali Filali‐Mouhim, Michael Ungar, Karen McEwan, Kathleen O'Grady, Donna Thomson, Parent Advisory Group, Patricia Lingley‐Pottie, Patrick McGrath, Lucyna M. Lach   +9 more
wiley   +1 more source

Characterization of Anticholinergic Medication Use and Its Associations With Everyday Memory Problems and Cognitive Decline in Autistic Adults With Higher Support Needs

Autism Research, EarlyView.
ABSTRACT Among older adults in the general population, medications with anticholinergic (AC) effects are associated with declines in cognitive functioning and with dementia and Alzheimer's disease. Autistic people have high rates of co‐occurring medical conditions and polypharmacy across the lifespan; thus, they may be at particularly high risk of ...
Goldie A. McQuaid, Nancy Raitano Lee, Gregory L. Wallace   +2 more
wiley   +1 more source

Blood pressure effects of SGLT2 inhibitors and GLP‐1 receptor agonists: Mechanisms, trial evidence and Real‐world data

British Journal of Clinical Pharmacology, EarlyView.
SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić, Yusuf Ziya Sener, Marijana Vučković, Joseph Edgar Blais, Almir Fajkić, Emina Sher, Mislav Radić, Josipa Radić   +7 more
wiley   +1 more source

How Did Women From South Asian Backgrounds and People Seeking Asylum and Refugees Look After Their Health and the Health of Others During the COVID-19 Pandemic? A Community Research Approach. [PDF]

Health Expect
Joseph O, Yahya NA, Butt L, Khan A, Khan S, O'Hara JK, Albutt A, Carter R, Haq R, Louch G.   +9 more
europepmc   +1 more source

Cost‐effectiveness of DPYD genotyping prior to fluoropyrimidine‐based treatment for colorectal cancer in Wales

British Journal of Clinical Pharmacology, EarlyView.
Abstract Background Regulatory guidance in the United Kingdom advises DPYD genotyping prior to fluoropyrimidine‐based treatment. This economic evaluation estimated the costs and outcomes associated with DPYD screening prior to prescribing fluoropyrimidines for colorectal cancer in Wales and also considers additional variants to those included in ...
Catrin O. Plumpton, Sian M. Morgan, Richard A. Adams, Samantha Cox, Angharad A. Rudkin, Megan Fealey, Craig Barrington, Michelle D. Wood, Dyfrig A. Hughes   +8 more
wiley   +1 more source

Perspectives and Needs Regarding Remote Monitoring Technologies Among South Asian Individuals Living With Long-Term Conditions in the United Kingdom: Semistructured Interview and Focus Group Study. [PDF]

JMIR Hum Factors
Ali SM, Masood Y, Staniland K, Dixon WG, van der Veer SN, Sanders C.   +5 more
europepmc   +1 more source

The effect of mild and moderate hepatic impairment on the pharmacokinetics, safety and tolerability of balcinrenone

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Balcinrenone (previously AZD9977) is a novel selective non‐steroidal mineralocorticoid receptor antagonist (MRA) with a differential mechanism of action relative to approved MRAs. The aim of this trial was to assess the pharmacokinetics, safety and tolerability of balcinrenone in participants with mild and moderate hepatic impairment ...
Anna L. Eriksson, Deeyen Karsanji, Bonifride Tuyishimire, Joanna Parkinson, Maria Heijer, Tadeusz Pawlik, Judith Hartleib‐Geschwindner, Maria Leonsson‐Zachrisson, Hans Ericsson   +8 more
wiley   +1 more source

COVID-19 Knowledge, Anxiety, and Access to Voluntary Counseling and Testing Among People With HIV During the COVID-19 Pandemic: Cross-Sectional Study. [PDF]

Asian Pac Isl Nurs J
Azizah SS, Yona S, Hanim RZ, Kurniawan R, Zahra AN.   +4 more
europepmc   +1 more source

MT‐RNR1 genotype testing for preventing aminoglycoside‐mediated ototoxicity: A guideline developed by the UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI‐PGx)

British Journal of Clinical Pharmacology, EarlyView.
Aminoglycosides are broad‐spectrum antibiotics used in the management of severe infections. Aminoglycosides are associated with nephrotoxicity and ototoxicity. Although dosing strategies such as once‐daily administration and therapeutic drug monitoring have reduced the incidence of nephrotoxicity, ototoxicity remains unpredictable and may occur at ...
John H. McDermott, Sian Hilton, Cinzia Dello Russo, Nicola Booth, Simon Drysdale, Philip Howard, Stephen Hughes, Mallinath Chakraborty, Helen McDevitt, Charlotte Alston, Maya Desai, Mike Beadsworth, Adam Reynolds, Serim Min, Katherine Payne, Munir Pirmohamed, William G. Newman   +16 more
wiley   +1 more source

Values, belief systems and mental health stigma - a scoping review and synthesis of quantitative evidence. [PDF]

BMC Psychiatry
Kummetat JL, Valerius K, Jesse H, Schomerus G, Speerforck S.   +4 more
europepmc   +1 more source