Results 21 to 30 of about 74,639 (307)

Nahivde İstishâb Yöntemi Örneğinde Aslın Dışına Çıkılan Durumlar

Şırnak Üniversitesi İlahiyat Fakültesi Dergisi, 2019
Arap dilcileri, Arapların kullanımlarından genel kurallara ulaşmak için çeşitli yöntem ve deliller kullanmış, ulaştıkları kuralları gerekçelendirmek ve tutarlılığını göstermek için çeşitli yollara başvurmuşlardır.
Yunus İnanç
doaj   +1 more source

Comparison of pseudocontinuous arterial spin labeling perfusion MR images and time-of-flight MR angiography in the detection of periictal hyperperfusion

eNeurologicalSci, 2020
Background: Magnetic resonance imaging (MRI), including perfusion MRI with three-dimensional pseudocontinuous arterial spin labeling (ASL) and diffusion-weighted imaging (DWI), are applied in the periictal (including ictal and postictal) detection of ...
Noritoshi Shirozu, Takato Morioka, So Tokunaga, Takafumi Shimogawa, Daisuke Inoue, Shoji Arihiro, Ayumi Sakata, Nobutaka Mukae, Sei Haga, Koji Iihara   +9 more
doaj   +1 more source

ASL mRNA-LNP Therapeutic for the Treatment of Argininosuccinic Aciduria Enables Survival Benefit in a Mouse Model

Biomedicines, 2023
Argininosuccinic aciduria (ASA) is a metabolic disorder caused by a deficiency in argininosuccinate lyase (ASL), which cleaves argininosuccinic acid to arginine and fumarate in the urea cycle.
Owen Daly, Azita Josefine Mahiny, Sara Majeski, Kevin McClintock, Julia Reichert, Gábor Boros, Gábor Tamás Szabó, Jonas Reinholz, Petra Schreiner, Steve Reid, Kieu Lam, Marlen Lepper, Melanie Adler, Tracy Meffen, James Heyes, Katalin Karikó, Pete Lutwyche, Irena Vlatkovic   +17 more
doaj   +1 more source

The “Communicative Processes-Based Model of Activity Sequencing’ (CPM): A Cognitively and Pedagogically Sound Alternative to the “Representation-Practice-Production Model of Activity Sequencing” (P-P-P) in ELT

Odisea, 2017
El modelo de secuenciación de actividades basado en procesos comunicativos (CPM): Una sólida alternativa al modelo Presentación-Práctica-Producción (P-P-P-) desde una perspectiva pedagógicay cognitiva.
Raquel Criado Sánchez
doaj   +1 more source

Assessment of Arterial Transit Time and Cerebrovascular Reactivity in Moyamoya Disease by Simultaneous PET/MRI

Diagnostics, 2023
We investigated the relationship between MRI-arterial spin labeling (ASL) parameters and PET-cerebral blood flow (CBF)/cerebrovascular reactivity (CVR) simultaneously obtained by PET/MRI in Moyamoya disease.
Kenji Takata, Hirohiko Kimura, Shota Ishida, Makoto Isozaki, Yoshifumi Higashino, Ken-Ichiro Kikuta, Hidehiko Okazawa, Tetsuya Tsujikawa   +7 more
doaj   +1 more source

Multiphase arterial spin labeling imaging to predict early recurrent ischemic lesion in acute ischemic stroke

Scientific Reports, 2022
In acute ischemic stroke (AIS), the hemodynamics around the lesion are important because they determine the recurrence or prognosis of the disease. This study evaluated the effects of perfusion deficits in multiphase arterial spin labeling (ASL) and ...
Ki-Woong Nam, Chi Kyung Kim, Byung-Woo Yoon, Inpyeong Hwang, Chul-Ho Sohn   +4 more
doaj   +1 more source

ASL Metabolically Regulates Tyrosine Hydroxylase in the Nucleus Locus Coeruleus

Cell Reports, 2019
Summary: Patients with germline mutations in the urea-cycle enzyme argininosuccinate lyase (ASL) are at risk for developing neurobehavioral and cognitive deficits. We find that ASL is prominently expressed in the nucleus locus coeruleus (LC), the central
Shaul Lerner, Elmira Anderzhanova, Sima Verbitsky, Raya Eilam, Yael Kuperman, Michael Tsoory, Yuri Kuznetsov, Alexander Brandis, Tevie Mehlman, Ram Mazkereth, Robert McCarter, Menahem Segal, Sandesh C.S. Nagamani, Alon Chen, Ayelet Erez, Fabienne Dietrich Alber, Talin Babikian, Heidi Bender, Christopher Boys, David Breiger, Corinna Buerger, Peter Burgard, Mina Nguyen-Driver, Benjamin Goodlett, Elizabeth Kerr, Casey Krueger, Eva Mamak, Jacqueline H. Sanz, David Schwartz, Susan Caudle, Arianna Stefanos, Rachel Tangen, Magdalena Walter, Susan Waisbren, Greta Wilkening   +34 more
doaj   +1 more source

COMT Val158Met Polymorphism Influences the Cerebral Blood Flow Changes Related to Psychomotor Retardation in Major Depressive Disorder

Neuropsychiatric Disease and Treatment, 2022
Yingying Yin,1,2 Chunming Xie,3 Haisan Zhang,4 Hongxing Zhang,5 Zhijun Zhang,3 Yonggui Yuan1,2 1Department of Psychosomatics and Psychiatry, ZhongDa Hospital, School of Medicine, Southeast University, Nanjing, 210009, People’s Republic of China ...
Yin Y, Xie C, Zhang H, Zhang H, Zhang Z, Yuan Y   +5 more
doaj  

Unlocking a Nitrosuccinate Lyase for Decarboxylative Enzymatic Hydronitration

Angewandte Chemie, EarlyView.
The nitrosuccinate lyase CreD catalyzes C–NO2 bond formation using nitrite in water and shows synthetic practicality with high turnover numbers up to 102,000. A combination of protein engineering and computational methods helped to reveal the mechanistic principles that underpin this unique enzymatic activity.
Matteo Aleotti, Hannah Dreisbach, Rémi Corlay, Clara Weber, Tamara Reiter, Wael Elaily, Bastian Daniel, Klaus Zangger, Pedro A. Sánchez‐Murcia, Mélanie Hall   +9 more
wiley   +2 more sources

Comparison of arterial spin labeling and dynamic susceptibility contrast perfusion MRI in patients with acute stroke. [PDF]

PLoS ONE, 2013
BACKGROUND: The aim of this study was to evaluate whether arterial spin labeling (ASL) perfusion magnetic resonance imaging (MRI) can reliably quantify perfusion deficit as compared to dynamic susceptibility contrast (DSC) perfusion MRI.
Yen-Chu Huang, Ho-Ling Liu, Jiann-Der Lee, Jen-Tsung Yang, Hsu-Huei Weng, Meng Lee, Mei-Yu Yeh, Yuan-Hsiung Tsai   +7 more
doaj   +1 more source