Results 201 to 210 of about 101,913 (345)

A mixed-methods study of patient perspectives on antiseizure medication discontinuation attempts after a period of seizure-freedom. [PDF]

open access: yesBMJ Neurol Open
Terman SW   +14 more
europepmc   +1 more source

Seizure relapse in new onset epilepsy: It is not always drug resistance

open access: yesEpilepsia, EarlyView.
Abstract Objective Seizure recurrence in new onset epilepsy (NOE) can result from various factors. Although drug ineffectiveness is frequently investigated, other causes—such as nonadherence, inadequate treatment, nonepileptic events (e.g., functional/dissociative), or acute symptomatic seizures—also impact patient outcomes.
Cecilia Catania   +11 more
wiley   +1 more source

A translational multimodal machine‐learning prototype predicting valproate response in epilepsy treatment

open access: yesEpilepsia, EarlyView.
Abstract Objective Epilepsy affects ~1% of the global population and often requires lifelong antiseizure medication (ASM) therapy. Valproic acid (VPA) is a commonly prescribed first‐line ASM, yet only approximately half of patients achieve sustained seizure freedom. Treatment selection remains largely empirical.
Simeon Platte   +15 more
wiley   +1 more source

ASMS awards

open access: yesJournal of the American Society for Mass Spectrometry, 2010
openaire   +1 more source

Clinical validation of a patient‐friendly saliva microsampling approach to monitor perampanel levels in people with epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Perampanel (PER) is a third‐generation antiseizure medication (ASM) with a well‐established concentration–effect relationship. Saliva represents a non‐invasive alternative to plasma for therapeutic drug monitoring (TDM) of PER, as it reflects the free plasma fraction.
Valentina Franco   +14 more
wiley   +1 more source

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