Results 271 to 280 of about 324,759 (334)

Expanding the scope of pediatric epilepsy surgery: Access, indications, and outcomes in a modern cohort

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Expanded indications, diagnostic tools, and treatment options have transformed the landscape of modern pediatric epilepsy surgery. Published real‐world experiences from large surgical cohorts are still needed. To close this gap, we evaluated access, indications, treatment, and outcomes in a contemporary pediatric epilepsy surgery ...
John R. McLaren   +12 more
wiley   +1 more source

An iEEG investigation on sex‐specific differences in seizure duration

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Male people with epilepsy (mPWE) are at higher risk for bilateral tonic–clonic seizures (BTCs) and sudden unexpected death in epilepsy (SUDEP) compared to female people with epilepsy (fPWE). Despite major clinical and personal implications, little is known about sex‐specific differences in seizure propagation and termination ...
Paula Albert I Gracenea   +4 more
wiley   +1 more source

Effectiveness of adjunctive low‐dose clobazam in adults with focal drug‐resistant epilepsy and incomplete response to cenobamate: A real‐world study

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Cenobamate (CNB) is a highly effective antiseizure medication (ASM) for focal drug‐resistant epilepsy (DRE); nevertheless, even with CNB treatment and optimized therapy, a substantial proportion of patients continued to experience seizures.
Ilaria Ciullo   +8 more
wiley   +1 more source

KCNQ2 neonatal epilepsy: Impact of prompt diagnosis and treatment, and early predictors of outcome severity

open access: yesEpilepsia Open, EarlyView.
The impact of prompt diagnosis and treatment, and early predictors of outcome severity in this cohort. Abstract Objective To determine whether prompt genetic diagnosis in children with KCNQ2 neonatal epilepsy enabling targeted therapy is associated with improved outcomes, and identify early predictors of developmental outcomes.
Trupti Jadhav   +17 more
wiley   +1 more source

Trends in paediatric antiseizure-medication use and costs in France, 2014-2023: a nationwide population-based analysis. [PDF]

open access: yesLancet Reg Health Eur
Nabbout R   +5 more
europepmc   +1 more source

Neuroanatomical correlates of neuropsychological dysfunction in pediatric pharmacoresistant epilepsy due to focal cortical dysplasia type II

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Children and adolescents with pharmacoresistant epilepsy (PRE) show marked individual cognitive and emotional variability not fully accounted for by demographic or clinical variables. This exploratory pilot study characterizes neuroanatomical abnormalities and their relationships with neuropsychological functioning in a pediatric ...
Ana Arenivas   +9 more
wiley   +1 more source

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