Results 91 to 100 of about 96,501 (333)

A Bioinstructive Injectable Hydrogel for Enhancing Intrinsic Regeneration through Cell Recruitment and Training

Advanced Science, EarlyView.
A bioinstructive injectable hydrogel enables sustained release of stromal cell–derived factor‐1 alpha (SDF‐1α) and stable retention of laminin through ionic and hydrophobic interactions. This dual‐signaling matrix promotes endogenous stem cell recruitment and training, supports angiogenesis, and enhances intrinsic regenerative processes in ischemic ...
Yurim Kim, Young‐Min Kim
wiley   +1 more source

IL‐4/STAT6‐signaling Influences Local Inflammation and Regeneration Processes During Acute Pancreatitis and Promotes Fibrosis by a Direct Activation of Pancreatic Fibroblasts During Chronic Pancreatitis

Advanced Science, EarlyView.
IL‐4/IL‐13/STAT6 signaling plays a crucial for the suppression of pro‐inflammation during acute pancreatitis and supports acinar cell regeneration but has only minor impact on fibrogenesis during chronic form of the disease. IL‐4/IL‐13 induce the expression of certain collagens directly in pancreatic fibroblasts via STAT6 activation, whereas ...
ElSheikh H, Salvers A, Piesker J, Buchholz S, Lange R, Ameling S, Steil L, Hammer E, Homuth G, Völker U, Bröker BM, Weiss FU, Sendler M, Glaubitz J   +13 more
wiley   +1 more source

Hubungan Kadar Vitamin C Plasma dengan Serangan Asma pada Anak

Sari Pediatri, 2016
Latar belakang. Banyak faktor yang dapat memicu serangan asma. Perhatian terhadap peran nutrisi antioksidan serta stres oksidatif pada kejadian asma beberapa tahun terakhir ini semakin meningkat.
Azwar Aruf, Roni Naning, Mei Neni Sitaresmi   +2 more
doaj   +1 more source

Remote homology searches identify bacterial homologues of eukaryotic lipid transfer proteins, including Chorein-N domains in TamB and AsmA and Mdm31p

BMC Molecular and Cell Biology, 2019
All cells rely on lipids for key functions. Lipid transfer proteins allow lipids to exit the hydrophobic environment of bilayers, and cross aqueous spaces.
T. Levine
semanticscholar   +1 more source

GOT1 Inhibition Induces Extracellular Matrix Remodeling in Pancreatic Cancer

Advanced Science, EarlyView.
Using tumor tissue engineering, we recreated pancreatic cancer and found that inhibiting glutamic‐oxaloacetic transaminase 1 (GOT1) induces extracellular matrix remodeling and secretome rewiring, as well as promotes cell death. ABSTRACT Pancreatic cancer cells rely on glutamine to sustain their survival in the stiff and poorly vascularized tumor ...
Rodrigo Curvello, Sandra Hauser, Michael Seifert, Christopher K. Barlow, Joel R. Steele, Emma Salisbury, Daniel Croagh, Kathryn S. Stok, Anna V. Taubenberger, Ralf B. Schittenhelm, Daniela Loessner   +10 more
wiley   +1 more source

Identificación y sensibilización a hongos ambientales en Lima, Perú

Revista Alergia México
Objetivo: Identificar y registrar las esporas de hongos más importantes captadas en nuestra estación de aerobiología, además reportar la prevalencia de sensibilización cutánea a estos alérgenos.
Oscar Manuel Calderón LLosa
doaj   +1 more source

Kepatuhan Berobat pada Pasien Asma Tidak Terkontrol dan Faktor-Faktor yang Berhubungan

Jurnal Penyakit Dalam Indonesia, 2015
Pendahuluan. Mencapai kontrol asma masih merupakan tujuan yang sulit dicapai sebagian besar pasien meskipun telah tersedia pedoman manajemen asma internasional dan terapi yang terbukti efektif.
Ferliani Ferliani, Heru Sundaru, Sukamto Koesnoe, Hamzah Shatri   +3 more
doaj   +1 more source

Targeting IL27RA Enhances Immunotherapy in Triple‐Negative Breast Cancer by Modulating Tumor Cells and the Tumor Microenvironment

Advanced Science, EarlyView.
IL27RA upregulation drives immune evasion in TNBC by suppressing MHC‐I expression and reprogramming T/NK‐cell states, establishing an immune‐excluded tumor phenotype. Targeting this epithelial‐intrinsic IL27RA–PI3K/AKT axis offers a promising strategy to overcome immunotherapy resistance.
Jiachi Xu, Qian Long, Meirong Zhou, Qitong Chen, Jing Peng, Qingchun Liang, Danhua Zhang, Hui Zhou, Wenjun Yi   +8 more
wiley   +1 more source

Peningkatan Kekuatan Otot Pernapasan dan Fungsi Paru Melalui Senam Asma Pada Pasien Asma

Jurnal Keperawatan Indonesia, 2011
Abstrak Pasien asma mengalami bronchospasme dan bronchokontriksi yang dapat menyebabkan penurunan fungsi pernapasan. Penelitian bertujuan mengidentifikasi pengaruh senam asma terhadap peningkatan kekuatan otot pernapasan dan fungsi paru pasien asma di ...
Camalia S. Sahat, Dewi Irawaty, Sutanto Priyo Hastono   +2 more
doaj   +1 more source

A DNA Tetrahedron Delivery Asiatic Acid to Reprogram Mitochondrial Metabolism for Promoting Bone Regeneration via STAT3 Phosphorylation

Advanced Science, EarlyView.
A hyaluronic acid methacrylate (HAMA) hydrogel incorporating DNA tetrahedrons loaded with Asiatic acid (TDN@AA) was developed. HM‐TDN@AA promotes angiogenesis of endothelial cells (ECs), inhibits osteoclastogenesis from bone marrow–derived macrophages (BMDMs), and enhances osteogenesis of mesenchymal stem cells (MSCs) via STAT3‐mediated mitochondrial ...
Yiwen Huang, Yiming Zhang, Yisheng Feng, Qixiang Yang, Beiyuan Gao, Haiyang Xu, Cheng Huang, Kaili Lin, Yuanzhi Xu, Peiqi Zhu   +9 more
wiley   +1 more source