Results 101 to 110 of about 26,411 (231)

Increased p‐Tau181 Levels After Overnight Wakefulness Are Associated With Neuroticism in Young Women

open access: yesJournal of Sleep Research, EarlyView.
Overnight wakefulness, mimicking night shift conditions, impaired morning vigilance in healthy, reproductive‐aged women, regardless of estradiol or neuroticism. However, the overnight wakefulness‐related rise in the Alzheimer's disease blood biomarker p‐Tau181 was greater in women with higher neuroticism, suggesting that neurobiological vulnerability ...
Diana A. Nôga   +14 more
wiley   +1 more source

Porphyromonas gingivalis GroEL exacerbates orthotopic allograft transplantation vasculopathy via impairment of endothelial cell function

open access: yesMolecular Oral Microbiology, EarlyView.
Abstract Orthotopic allograft transplantation (OAT) is a significant approach to addressing organ failure. However, persistent immune responses to the allograft affect chronic rejection, which induces OAT vasculopathy (OATV) and organ failure. Porphyromonas gingivalis can infiltrate remote organs via the bloodstream, thereby intensifying the severity ...
Chien‐Sung Tsai   +7 more
wiley   +1 more source

Porphyromonas gingivalis GroEL accelerates abdominal aortic aneurysm formation by matrix metalloproteinase‐2 SUMOylation in vascular smooth muscle cells: A novel finding for the activation of MMP‐2

open access: yesMolecular Oral Microbiology, EarlyView.
Abstract Infection is a known cause of abdominal aortic aneurysm (AAA), and matrix metalloproteases‐2 (MMP‐2) secreted by vascular smooth muscle cells (SMCs) plays a key role in the structural disruption of the middle layer of the arteries during AAA progression.
Yi‐Wen Lin   +6 more
wiley   +1 more source

Hubungan Tingkat Pengetahuan Mengenai Asma dengan Tingkat Kontrol Asma

open access: yesJurnal Kesehatan Andalas, 2014
AbstrakKontrol gejala asma yang baik merupakan tujuan pengobatan bagi pasien asma. Pengobatan medikamentosa dan self management dibutuhkan untuk mencapai kontrol asma.
Katerine ., Irvan Medison, Erlina Rustam
doaj  

Emotions in Meaning‐Making: Toward a Sociological Theory of Cathexis

open access: yesSociological Forum, EarlyView.
ABSTRACT The role of emotion in meaning‐making remains undertheorized in cultural sociology. This article argues that emotions and affect are intrinsic to meaning‐making and proposes cathexis—the attachment of emotions generated in social interaction to objects, symbols, and ideas—as the fundamental mechanism by which emotions co‐constitute cultural ...
Dmitry Kurakin
wiley   +1 more source

HUBUNGAN DERAJAT ASMA PERSISTEN DAN KUALITAS HIDUP PASIEN ASMA DINILAI DENGAN ASTHMA QUALITY OF LIFE QUESTIONNAIRE (AQLQ)

open access: yesJurnal Vokasi Kesehatan, 2015
: The Relationship Between Degree Of Persistent Asthma And Quality Of Life In Asthma Patient That Measured By Asthma Quality Of Life Questionnaire. The aims of this study were to determine the quality of life in asthma patients in Poli Paru dr.
M. Jahari Supianto   +2 more
doaj  

Moderate maternal nutrient restriction alters type II alveolar epithelial cell density in the non‐human primate fetal lung

open access: yesExperimental Physiology, EarlyView.
Abstract Restriction of fetal substrate supply has an adverse effect on surfactant maturation in the lung and thus affects the transition from in utero placental oxygenation to pulmonary ventilation ex utero. However, the consequences of reduced fetal substrate supply are dependent on the timing of gestation, severity and duration.
Mitchell C. Lock   +5 more
wiley   +1 more source

Cellular microenvironment of erythropoietin‐producing cells in hypoxic and injured mouse kidneys

open access: yesExperimental Physiology, EarlyView.
Abstract The main sources of circulating erythropoietin (Epo) in the adult are kidney Norn cells, a recently identified interstitial cell type capable of becoming renal Epo‐producing (REP) cells following a local decrease in tissue oxygenation. REP cells are restricted to small clusters in the corticomedullary border region, suggesting that their ...
Olga M. Lempke   +3 more
wiley   +1 more source

Endothelial‐to‐mesenchymal transition in the fetoplacental macrovasculature and microvasculature in pregnancies complicated by gestational diabetes

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Transforming growth factor (TGF)‐β2 and interleukin (IL)‐1β induced morphological and molecular changes consistent with endothelial‐to‐mesenchymal transition (EndMT) in HUVECs isolated from both pregnancies complicated by gestational diabetes (GDM) and non‐GDM pregnancies.
Abigail R. Byford   +9 more
wiley   +1 more source

Computational modelling of cardiac fibroblast signalling reveals a key role for Ca2+ in driving atrial fibrillation‐associated fibrosis

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend A pre‐existing fibroblast signalling model was enhanced by integrating atrial‐specific components and reactions linked to atrial fibrosis and atrial fibrillation (AF). The analysis highlights the central role of Ca2⁺ signalling in driving profibrotic responses to AF‐relevant stimuli, angiotensin‐II and transforming growth factor ...
Najme Khorasani   +5 more
wiley   +1 more source

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