Results 231 to 240 of about 96,501 (333)

Fibroblast‐specific palladin drives kidney fibrosis via MRTF–SRF signaling

open access: yesThe Journal of Pathology, Volume 268, Issue 1, Page 40-53, January 2026.
Abstract Fibrosis is a common end‐stage pathway of progressive chronic kidney diseases. Previously we demonstrated that myocardin‐related transcription factor (MRTF)–serum response factor (SRF) signaling drives the expression of fibrosis‐related molecules through actin cytoskeleton dynamics in renal fibroblasts.
Naoki Yamamoto   +27 more
wiley   +1 more source

Comparison of Insertion Difficulties and Performance of Thoracoamniotic Shunts for Fetal Hydrothorax

open access: yesPrenatal Diagnosis, Volume 46, Issue 1, Page 105-113, January 2026.
ABSTRACT Objective This study compared insertion difficulties, shunt failure, reintervention rates, maternal adverse events, and neonatal outcomes among different shunt types used in fetal hydrothorax. Method A retrospective multicenter cohort study (2012–2022) was conducted across 12 international centers.
Tess T. Treurniet   +26 more
wiley   +1 more source

[Consensus document for Severe Asthma. 2025 Update]. [PDF]

open access: yesOpen Respir Arch
Álvarez-Gutiérrez FJ   +27 more
europepmc   +1 more source

Do Children and Parents Agree on the Level of Asthma Control? A Systematic Review

open access: yesPediatric Pulmonology, Volume 61, Issue 1, January 2026.
ABSTRACT Background Asthma is a prevalent chronic condition in children, and is often not sufficiently controlled. Children and parents may have a different interpretation of the level of asthma control, which can lead to suboptimal treatment. This systematic review aims to synthesize literature regarding concordance between children and their parents ...
Sara Bousema   +5 more
wiley   +1 more source

Dynamic Regulation of Collagens, Proteases, Their Inhibitors, and Cell Death in Experimental Asthma in Mice

open access: yesAllergy, Volume 81, Issue 1, Page 170-184, January 2026.
This study investigates airway remodeling in acute and chronic experimental asthma models induced by house dust mite extract to elucidate inflammatory and structural changes. Two acute T2‐low models demonstrated pronounced airway inflammation characterized by goblet cell hyperplasia, collagen deposition, and significant upregulation of extracellular ...
Marlena Tynecka   +17 more
wiley   +1 more source

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