Results 41 to 50 of about 26,411 (231)

Early Radiation Therapy Response Assessment Using Multi‐Scale Photoacoustic Imaging

Advanced Science, EarlyView.
Tomographic and mesoscopic photoacoustics capture intratumoural features of radioresistance and response. ABSTRACT There is a critical unmet clinical need to identify biomarkers that predict and detect radiation therapy (RT) response in cancer. Using the unique capabilities of multi‐scale photoacoustic imaging (PAI) to depict tumor oxygenation and ...
Thierry L. Lefebvre, Mariam‐Eleni Oraiopoulou, Ellie V. Bunce, Thomas R. Else, Lorna C. Wright, Monika A. Golinska, Lina Hacker, Cara Brodie, Steven Kupczak, Yi Cheng, Lisa Young, Paul W. Sweeney, Sarah E. Bohndiek   +12 more
wiley   +1 more source

Estudio aerobiológico en Lima, Perú. ¿Tipuana- Tipu, tal vez un nuevo alérgeno?

Revista Alergia México
Objetivo: Reportar al polen de Tipuana tipu como un nuevo alérgeno capaz de desencadenar síntomas alérgicos.  Métodos: Los conteos de polen se realizaron según la técnica estandarizada con un equipo colector tipo Hirst, Burkard spore trap for seven days,
Oscar Manuel Calderón LLosa
doaj   +1 more source

Bioprinting of Microtissues Within Mechanically Tunable Support Baths to Engineer Anisotropic Musculoskeletal Tissues

Advanced Science, EarlyView.
This study presents a novel 4D bioprinting platform for engineering biomimetic musculoskeletal grafts. By tuning the mechanical properties of support baths, we enhance tissue fusion, collagen alignment, and cell differentiation. Using this strategy, we successfully fabricate scaled‐up, anisotropic tissues such as meniscus, articular cartilage, and ...
Francesca D. Spagnuolo, Gabriela S. Kronemberger, Daniel J. Kelly   +2 more
wiley   +1 more source

Fibroblast Activation Protein Promotes Thoracic Aortic Dissection via PLAUR/ITGB1‐Mediated Pro‐inflammatory Macrophage Polarization

Advanced Science, EarlyView.
This study reveals that FAP promotes thoracic aortic dissection (TAD) through a nonenzymatic mechanism involving fibroblast‐macrophage crosstalk via the FAP/PLAUR/ITGB1/FAK axis. Targeting this pathway might offer a promising therapeutic strategy for TAD.
Hongqiao Zhu, Jianlie Wu, Ziyi Xu, Yifei Pei, Zaiping Jing, Jian Zhou, Rui Feng, Junjun Liu   +7 more
wiley   +1 more source

Avaliação do controle da asma entre diferentes medidas e avaliação da capacidade de exercício funcional em crianças e adolescentes com asma [PDF]

Jornal Brasileiro de Pneumologia
RESUMO Objetivo Avaliar a concordância entre as medidas de controle da asma e a capacidade de exercício funcional em crianças e adolescentes com asma não controlada e controlada. Métodos Selecionamos crianças e adolescentes com asma de 7 a 17 anos, que
Natasha Yumi Matsunaga, Caio de Oliveira, Livea Gianfrancesco, Marina Simões Oliveira, Maria Cristina Ribeiro dos Santos Simões, André Moreno Morcillo, José Dirceu Ribeiro, Maria Angela Gonçalves de Oliveira Ribeiro, Adyléia Aparecida Dalbo Contrera Toro   +8 more
doaj   +3 more sources

An Insulin‐Exosome‐TNFAIP8 Axis Drives Stromal Fibrosis and Therapeutic Resistance in Pancreatic Cancer

Advanced Science, EarlyView.
In pancreatic ductal adenocarcinoma (PDAC), insulin is associated with activation of PI3K/AKT–RAB3A signaling and enhanced secretion of TNFAIP8‐enriched exosomes from tumor cells. Uptake of these exosomes by fibroblasts is linked to TRIM21‐dependent STAT1 degradation and the emergence of myofibroblastic CAF–associated features, accompanied by increased
Zhenyu Li, Li Chen, Tao Wang, Haiyang Jiang, Huijuan Wang, Mengyu Li, Guanpeng Xie, Chunhua Xi, Han Yan, Chunhui Lu, Chenchen Li, Hanyu Zhu, Feihu Sun, Lingdi Yin, Jun Yu, Yi Miao   +15 more
wiley   +1 more source

HUBUNGAN OBESITAS DAN KEJADIAN ASMA PADA ANAK USIA 13-14 TAHUN

Jurnal Kedokteran Diponegoro, 2019
Latar Belakang: Asma merupakan penyakit saluran respiratori kronik yang mengakibatkan obstruksi jalan napas dengan gejala utama wheezing. Penyakit ini masih menjadi masalah kesehatan masyarakat di seluruh dunia, terutama di negara berkembang.
Taufiq Pratama Wijayanto, MS Anam MS Anam, Nahwa Arkhaesi   +2 more
doaj   +1 more source

Decoding the Integrated Stress Response of Pancreatic Cancer: Identifying a Serine‐dependent Tumor Subset Under Metabolic Relationships With CAFs.

Advanced Science, EarlyView.
Researchers identified a pancreatic cancer subset with low global protein synthesis but heightened translation of stress‐response genes like ATF4, rendering cells resistant to chemotherapy and apoptosis. These tumors depend on serine and cysteine from surrounding cancer‐associated fibroblasts (CAFs), which shift to produce serine by curbing collagen ...
Sauyeun Shin, Mehdi Liauzun, Jacobo Solorzano, Morgane Le Bras, Christine Jean, Benjamin Fourneaux, Margaux Dore, Lea Fevrier, Ismahane Belhabib, Alexia Brunel, Cindy Neuzillet, Marion Larroque, Carine Joffre, Stephane Rocchi, Nicolas Fraunhoffer, Aurelie Perraud, Muriel Mathonnet, Vera Pancaldi, Laetitia Linares, Juan Iovanna, Nelson Dusetti, Ola Larsson, Remy Nicolle, Stephane Pyronnet, Corinne Bousquet, Yvan Martineau   +25 more
wiley   +1 more source

Factores sociodemográficos y su relación con el nivel de control del asma en pacientes pediátricos del Instituto Nacional de Salud del Niño de Perú

Revista Alergia México, 2018
Antecedentes: La monitorización del asma en pediatría se basa en establecer el nivel de control de la enfermedad mediante cuestionarios como el Asthma Control Test (ACT).
César Galván-Calle, Ricardo Muñoz-León, David García-Gomero, Edgar Matos-Benavides, Wilmer Córdova-Calderón, María López-Talledo   +5 more
doaj  

Hubungan Eosinofil dan Neutrofil Darah Tepi terhadap Derajat Keparahan Asma pada Pasien Asma di Bagian Rawat Inap Paru RSUP Dr. M. Djamil Padang Periode 2010 – 2013

Jurnal Kesehatan Andalas, 2017
Asma adalah penyakit inflamasi kronik yang ditandai dengan adanya infiltrasi sel-sel radang, termasuk eosinofil dan neutrofil. Kedua sel ini dapat melepaskan protein-protein yang mempunyai efek toksik langsung terhadap epitel saluran nafas sehingga ...
Dwiyana Roselin, Eryati Darwin, Irvan Medison   +2 more
doaj   +1 more source