Results 21 to 30 of about 2,135 (156)

Effect of Different Irrigation Levels and Methods of Humic Acid Addition on Growth, Yield and Storability of Garlic [PDF]

Journal of Plant Production, 2021
A field experiment was carried out to study the effect of different levels of irrigation at 40%, 60% and 80% of available soil moisture depletion (ASMD) and humic acid application methods (without, soil application, foliar application and soil ...
T. Deshesh, Sayed Rizk
doaj   +1 more source

Plasma lyso-sphingomyelin levels are positively associated with clinical severity in acid sphingomyelinase deficiency

Molecular Genetics and Metabolism Reports, 2021
Introduction: A reliable biomarker is urgently needed in the diagnosis and management of acid sphingomyelinase deficiency (ASMD, also known as Niemann Pick A, A/B, and B).
Margo Sheck Breilyn, Wenyue Zhang, Chunli Yu, Melissa P. Wasserstein   +3 more
doaj   +1 more source

YIELD AND WATER RELATIONS OF WHEAT UNDER TILLAGE SYSTEMS AND IRRIGATION REGIMES AT FAYOUM. [PDF]

Fayoum Journal of Agricultural Research and Development, 2006
Two field experiments were conducted at Fayoum Agric. Res.Station (Kom Osheem) during 2002/2003 and 2003/2004 seasons tostudy the effect of tillage operations (number of ploughing) andirrigation at different levels of available soil moisture (ASMD ...
Mohamed R.K Ashry, Kamal M.R Youssef
doaj   +1 more source

Antiviral Therapy and Post-Resection Outcomes in Patients With Hepatitis B Virus-Related Hepatocellular Carcinoma. [PDF]

Aliment Pharmacol Ther
In 902 patients with HBV‐related HCC undergoing curative resection, antiviral regimens (ETV, TDF, TAF) showed comparable recurrence‐free survival. However, TDF was independently associated with improved overall survival compared with ETV. ABSTRACT Background & Aims The comparative outcomes of entecavir (ETV), tenofovir disoproxil fumarate (TDF), and ...
Jeong J, Hong JP, Kim DY, Lee JS, Kim MN, Kim SU, Kim BK, Park JY, Kim DY, Ahn SH, Lee HW.   +10 more
europepmc   +2 more sources

Urogenital Infection Risk Associated With SGLT2 Inhibitors Versus DPP-4 Inhibitors in Type 2 Diabetes and Chronic Kidney Disease: A Nationwide Target Trial Emulation. [PDF]

Clin Pharmacol Ther
Although sodium‐glucose cotransporter‐2 inhibitors (SGLT2i) are recommended for patients with type 2 diabetes mellitus (T2DM) and chronic kidney disease (CKD), concerns regarding urogenital infections persist. Therefore, we evaluated the risk of urinary tract infection (UTI) and genital tract infection (GTI) after SGLT2i initiation in this population ...
Ah YM, Nam J, Youn JW, Yu YM, Kang S.
europepmc   +2 more sources

Impact and burden of acid sphingomyelinase deficiency from a patient and caregiver perspective

Scientific Reports, 2021
Acid sphingomyelinase deficiency (ASMD), historically known as Niemann–Pick disease (NPD) types A, A/B, and B, is a rare, progressive, potentially fatal lysosomal storage disease with a spectrum of phenotypes.
Robin Pokrzywinski, Asha Hareendran, Luba Nalysnyk, Sandy Cowie, Joslyn Crowe, Justin Hopkin, Dhaivat Joshi, Ruth Pulikottil-Jacob   +7 more
doaj   +1 more source

Consensus clinical management guidelines for acid sphingomyelinase deficiency (Niemann–Pick disease types A, B and A/B)

Orphanet Journal of Rare Diseases, 2023
Background Acid Sphingomyelinase Deficiency (ASMD) is a rare autosomal recessive disorder caused by mutations in the SMPD1 gene. This rarity contributes to misdiagnosis, delayed diagnosis and barriers to good care.
Tarekegn Geberhiwot, Melissa Wasserstein, Subadra Wanninayake, Shaun Christopher Bolton, Andrea Dardis, Anna Lehman, Olivier Lidove, Charlotte Dawson, Roberto Giugliani, Jackie Imrie, Justin Hopkin, James Green, Daniel de Vicente Corbeira, Shyam Madathil, Eugen Mengel, Fatih Ezgü, Magali Pettazzoni, Barbara Sjouke, Carla Hollak, Marie T. Vanier, Margaret McGovern, Edward Schuchman   +21 more
doaj   +1 more source

From Biological Mechanisms to Causal Inference: Quantitative Systems Pharmacology and Causal Frameworks in Drug Development. [PDF]

Clin Pharmacol Ther
Digital patients and in silico clinical trials offer new opportunities to advance pharmacological research, clinical development, and regulatory decision‐making by enabling the simulation of treatment effects prior to testing in patients. Among the most promising of these opportunities is the combined use of quantitative systems pharmacology (QSP) and ...
Klabunde T, Hernandez R, van der Graaf PH, Andreani T.   +3 more
europepmc   +2 more sources

EFFECTS OF AVAILABLE SOIL MOISTURE DEPLETION LEVELS AND SOME FOLIAR – SPRAYED ORGANIC ACIDS ADDITIONS ON YIELD AND SOME CROP WATER RELATIONS OF DRIP-IRRIGATED MAIZE [PDF]

Journal of Soil Sciences and Agricultural Engineering, 2012
    A field experiment was conducted at El- Areish Agricultural Research Station, North Sinai Governorate, Egypt, during 2010 and 2011 summer seasons to study the effect of available soil moisture depletion levels and foliar spray with some organic acids
E. A. M. Osman, T. A. A. Eid, K. M. Abd El-Latif   +2 more
doaj   +1 more source

Maternal Dipyrone Exposure and Risk of Major Congenital Malformations, Adverse Perinatal and Postnatal Outcomes: A Population-Based Cohort Study. [PDF]

Clin Pharmacol Ther
Pain and fever are common in pregnancy. Dipyrone is widely used in Europe, Latin America, and parts of Asia, but is banned in other countries due to concerns about agranulocytosis. Evidence on its safety in pregnancy remains limited and inconsistent. This study aimed to evaluate whether maternal dipyrone use during the first‐ and third‐trimesters is ...
Shitrit IB, Idan D, Hasidim AA, Michael T, Levy A, Pariente G, Lunenfeld E, Daniel S.   +7 more
europepmc   +2 more sources