Results 11 to 20 of about 4,741 (219)

OCTN2 Activates a Non-Canonical Carnitine Metabolic Pathway to Promote MASH-HCC Progression and Immunotherapy Resistance. [PDF]

Adv Sci (Weinh)
In non‐MASH‐HCC, L‐carnitine promotes tumor progression primarily through its classical role in enhancing fatty acid oxidation (FAO). However, in MASH‐HCC, where FAO is markedly suppressed, L‐carnitine shifts from this canonical function to serve instead as an intracellular acetyl group buffer.
Xia C, Zhang X, Li J, Xu N, Hu S, Lu Q, Li Y, Xiao T, Li X, Wang X, Xu K, Liang D.   +11 more
europepmc   +2 more sources

Skeletal Muscle Biomarkers of Amyotrophic Lateral Sclerosis: A Large-Scale, Multi-Cohort Proteomic Study. [PDF]

Ann Neurol
Objective Biomarkers with clear contexts of use are important tools for amyotrophic lateral sclerosis (ALS) therapy development. Understanding their longitudinal trajectory in the untreated state is key to their use as potential markers of pharmacodynamic response.
Dergai O, Wuu J, Koziczak-Holbro M, Malaspina A, Granit V, Hernandez JP, Cooley A, Sachdev R, Yu L, Bidinosti M, Flotte L, Nash M, Jennings LL, Berry JD, Bruijn LI, Brachat S, Benatar M.   +16 more
europepmc   +2 more sources

Volcanic magma reservoir imaged as a low-density body beneath Aso volcano that terminated the 2016 Kumamoto earthquake rupture [PDF]

, 2016
Additional file 2: Figure S2. Calculated density contrast models beneath Aso volcano in horizontal slices at depths of 3.1, 4.9, and 8.2 km: (a), (b), (c), (d), (e), and (f) correspond to density contrasts of ±0.15, ±0.20 ±0.25, ±0.30, ±0.35, and ±0.40 g/
Ayumu Miyakawa, Makoto Otsubo, Ryo Okuwaki, Shimpei Uesawa, Tatsuya Sumita, Yasukuni Okubo, Yuji Yagi   +6 more
core   +4 more sources

Distribution and Eruptive Volume of Aso-4 Pyroclastic Density Current and Tephra Fall Deposits, Japan: A M8 Super-Eruption

Frontiers in Earth Science, 2020
Estimations of the distribution and eruptive volume of large-scale pyroclastic density current (PDCs) and tephra fall deposits are essential for evaluation of the affected area, long-term volcanic hazards assessments, volcanic activity, and geophysical ...
Shinji Takarada, Hideo Hoshizumi
doaj   +1 more source

Hydrothermal system of the active crater of Aso volcano (Japan) inferred from a three-dimensional resistivity structure model

Earth, Planets and Space, 2019
During the past two decades, studies of the Aso volcano in Japan have improved our understanding of the shallow hydrothermal system that exists beneath the active crater of this volcano.
Wataru Kanda, Mitsuru Utsugi, Shinichi Takakura, Hiroyuki Inoue   +3 more
doaj   +1 more source

The 2018 phreatic eruption at Mt. Motoshirane of Kusatsu–Shirane volcano, Japan: eruption and intrusion of hydrothermal fluid observed by a borehole tiltmeter network

Earth, Planets and Space, 2021
We estimate the mass and energy budgets for the 2018 phreatic eruption of Mt. Motoshirane on Kusatsu–Shirane volcano, Japan, based on data obtained from a network of eight tiltmeters and weather radar echoes.
Akihiko Terada, Wataru Kanda, Yasuo Ogawa, Taishi Yamada, Mare Yamamoto, Takahiro Ohkura, Hiroshi Aoyama, Tomoki Tsutsui, Shin’ya Onizawa   +8 more
doaj   +1 more source

Mercury fluxes from volcanic and geothermal sources: an update [PDF]

, 2014
We review the state of knowledge on global volcanogenic Hg emissions to the atmosphere and present new data from seven active volcanoes (Poás, Rincón de la Vieja, Turrialba, Aso, Mutnovsky, Gorely and Etna) and two geothermal fields (Las Pailas and Las
Avard, G, Bagnato, E, Enrico, M, Fu, X, Martinez, MC, Sonke, JE, Sprovieri, M, TAMBURELLO, Giancarlo   +7 more
core   +1 more source

Gas flow dynamics in the conduit of Strombolian explosions inferred from seismo-acoustic observations at Aso volcano, Japan

Earth, Planets and Space, 2019
Strombolian explosions are one of the most studied eruptive styles and are characterized by intermittent explosions. The mechanism of a Strombolian explosion is modeled as a large gas pocket (slug) migrating through the magma conduit and then bursting at
Kyoka Ishii, Akihiko Yokoo, Tsuneomi Kagiyama, Takahiro Ohkura, Shin Yoshikawa, Hiroyuki Inoue   +5 more
doaj   +1 more source

Shallow volcanic reservoirs and pathways beneath Aso caldera revealed using ambient seismic noise tomography

Earth, Planets and Space, 2018
Imaging the shallow velocity structures beneath Aso caldera is necessary to further understand volcanism at the volcano and in the region. The network for monitoring Aso volcano has been progressively renewed and upgraded with denser and more modern ...
Yu-Chih Huang, Takahiro Ohkura, Tsuneomi Kagiyama, Shin Yoshikawa, Hiroyuki Inoue   +4 more
doaj   +1 more source

Thermal Activity Monitoring of an Active Volcano Using Landsat 8/OLI-TIRS Sensor Images: A Case Study at the Aso Volcanic Area in Southwest Japan

Geosciences, 2017
Thermal remote sensing is currently an emerging technique for monitoring active volcanoes around the world. The study area, the Aso volcano, is currently the most active and has erupted almost every year since 2012.
Md. Bodruddoza Mia, Yasuhiro Fujimitsu, Jun Nishijima   +2 more
doaj   +1 more source