Results 41 to 50 of about 4,741 (219)

Neuid: A Novel Neuron‐Enriched LncRNA that Connects Epigenetic Gene Silencing to Alzheimer's Disease

Advanced Science, EarlyView.
ABSTRACT The increasing evidence that non‐coding RNAs can become deregulated during pathogenesis is dramatically expanding the space for drug discovery beyond the protein‐coding genome. Long noncoding RNAs (lncRNAs) are emerging as key regulators of cellular function, yet most remain uncharacterized.
Ranjit Pradhan, Zorica Petrovic, M. Sadman Sakib, Sophie Schröder, Dennis Manfred Krüger, Tonatiuh Pena, Eren Diniz, Susanne Burkhardt, Anna‐Lena Schütz, Verena Gisa, Iga Grzadzielewska, Karl Toischer, Thor D. Stein, Jan Krzysztof Blusztajn, Ivana Delalle, Jelena Radulovic, Farahnaz Sananbenesi, Andre Fischer   +17 more
wiley   +1 more source

Variation of volcanic gas composition during the eruptive period in 2014–2015 at Nakadake crater, Aso volcano, Japan

Earth, Planets and Space, 2018
Volcanic gas composition measurement by Multi-GAS was repeated during the eruptive period in 2014–2015 as well as the quiet period preceding the eruption at Nakadake crater, Aso volcano.
Hiroshi Shinohara, Akihiko Yokoo, Ryunosuke Kazahaya   +2 more
doaj   +1 more source

The 1953 Eruption of Volcano Aso, Kyushu, Japan

The Journal of the Geological Society of Japan, 1954
Volcano Aso which had been almost dormant since April, 1952, suddenly became active at the end of April, 1953., Repeated explosions occurred in Nakadake crater, the first of which occurred at 11h31m, April 27, the second at 02h16m, April 28, the third at 22h56m, April 29, and the fourth at 10h35m hours, May 4., Two or three additional explosions ...
Sadakatu TANEDA, Yukio MATUMOTO
openaire   +2 more sources

Mitochondrial CircRNA CircMT‐RNR2 Safeguards Antioxidant Defense to Support Fibroblast Functions in Wound Repair

Advanced Science, EarlyView.
CircMT‐RNR2 promotes wound healing by enhancing fibroblast proliferation, migration, contraction, and extracellular matrix (ECM) production. It sustains mitochondrial redox balance by stabilizing the antioxidant protein PRDX3, thereby reducing ROS‐induced damage. In diabetic foot ulcers, hypoxia, hyperglycemia, and reduced FGF2 and EGF expression lower
Guanglin Niu, Jennifer Geara, Yongjian Chen, Lihua Luo, Yanwei Xiao, Zhuang Liu, Margaux Gaborieau, Ling Pan, Edmund Loh, Dongqing Li, Pehr Sommar, Aoxue Wang, Xiaowei Zheng, Ning Xu Landén   +13 more
wiley   +1 more source

Method for estimating the end of the deflation initiated in 2014 at Sinabung volcano, Indonesia, under the assumption that the magma behaves as a Bingham fluid

Earth, Planets and Space, 2018
We herein estimated the end of the ongoing deflation at Sinabung volcano, Indonesia, which began in 2014 under the assumption that the magma is incompressible and behaves as a Bingham fluid.
Kohei Hotta, Masato Iguchi, Takahiro Ohkura, Muhamad Hendrasto, Hendra Gunawan, Umar Rosadi, Estu Kriswati   +6 more
doaj   +1 more source

Constraints on the Timing of Explosive Volcanism at Aso and Aira Calderas (Japan) Between 50 and 30 ka: New Insights From the Lake Suigetsu Sedimentary Record (SG14 Core)

Geochemistry, Geophysics, Geosystems, 2020
Volcanoes in the East Asian/Pacific region have been the source of some of the largest magnitude eruptions during the Late Quaternary, and accurately evaluating their eruptive histories is essential for hazard assessments.
D. McLean, P. G. Albert, T. Suzuki, T. Nakagawa, J.‐I. Kimura, Q. Chang, Y. Miyabuchi, C. J. Manning, A. MacLeod, S. P. E. Blockley, R. A. Staff, K. Yamada, I. Kitaba, A. Yamasaki, T. Haraguchi, J. Kitagawa, SG14 Project Members, V. C. Smith   +17 more
doaj   +1 more source

Premature polyadenylation-mediated loss of stathmin-2 is a hallmark of TDP-43-dependent neurodegeneration. [PDF]

, 2019
Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are associated with loss of nuclear transactive response DNA-binding protein 43 (TDP-43).
Artates, Jon W, Baughn, Michael W, Beccari, Melinda S, Bennett, C Frank, Cleveland, Don W, Da Cruz, Sandrine, Drenner, Kevin, Freyermuth, Fernande, Lagier-Tourenne, Clotilde, Lin, Nianwei, López-Erauskin, Jone, McMahon, Moira A, Melamed, Ze'ev, Ohkubo, Takuya, Ravits, John, Rigo, Frank, Rodriguez, Maria, Sun, Ying, Wu, Dongmei, Zhang, Ouyang   +19 more
core  

Studies on the Volcanic Prod_??_cts of Aso Volcano. X

NIPPON KAGAKU KAISHI, 1943
湯の谷火口瀬にある間歇泉の噴騰繼續中に於ける噴湯の水素イオン濃度及び含有固形物量の時間的變化を檢し,火口跡内外にある所謂地獄の湛水涌泉,附近の河川の流水,及び内牧温泉の涌泉等の水素イオン濃度を測定しそれらの結果に就て考察した.
openaire   +9 more sources

VLF -MT Survey around Nakadake crater at Aso Volcano

IOP Conference Series: Earth and Environmental Science, 2016
Shallow resistivity structure around Nakadake craters has been revealed by extensive VLF- MT survey from August to October 2006. This structure comprises a varied resistivity value at the upper and bottom layer of the western flank of craters; a conductive upper layer at the fourth Crater; and a resistive upper layer at southern part of craters.
Harja, A., Srigutomo, W., Tanaka, Y., Kagiyama, T., Sutarno, D.   +4 more
openaire   +1 more source

Ascites circRNA ASCOR Drives Platinum Resistance of High‐Grade Serous Ovarian Cancer by Facilitating RPA1 Nuclear Translocation

Advanced Science, EarlyView.
High‐grade serous ovarian carcinoma (HGSOC) is plagued by platinum resistance, with malignant ascites closely linked to poor outcomes. Here, we identify ASCOR, a circRNA enriched in ascites small extracellular vesicles (sEVs) from platinum‐resistant HGSOC patients, as a predictor of poor survival. ASCOR enhances platinum resistance in vitro and in vivo
Hanyuan Liu, Chenchen Zhu, Xuelin Yao, Yi Liu, Jing Zhu, Yuebo Li, Hanjie Xu, Cheng Peng, Ge Shan, Liang Chen, Ying Zhou   +10 more
wiley   +1 more source