Results 21 to 30 of about 83,960 (169)

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Clean Up Behind You ‐ Novel Patterning Approach for Solid Immersion Lenses

open access: yesAdvanced Functional Materials, EarlyView.
A focused ion beam (FIB) milling strategy enables rapid fabrication of solid immersion lenses (SILs) with smooth, debris‐free surfaces eliminating the need for post‐processing. The optimized pattern improves efficiency and surface quality. SILs containing NV centers are also investigated, confirming the technique's suitability for quantum and photonic ...
Aleksei Tsarapkin   +10 more
wiley   +1 more source

Amido‐Amine Co(II) Precursor‐Based Atomic/Molecular Layer Deposition Processes for Cobalt‐Organic Thin Films and Their Thermal Conversion to CoO Thin Films

open access: yesAdvanced Materials Technologies, EarlyView.
Three new atomic/molecular layer deposition processes are developed for Co‐organic thin films using a promising all‐nitrogen‐coordinated cobalt precursor. The study examines film growth, reaction mechanisms, chemical stability, and decomposition pathways of the resulting films through extensive characterization techniques and DFT calculations ...
Topias Jussila   +9 more
wiley   +1 more source

Igualdad, justicia y compromiso social. El plan de igualdad de la Federación ENLACE

open access: yesOñati Socio-Legal Series, 2012
The First Gender Equality Programme of ENLACE Federation is the result of the commitment that we always had with Justice, Social Equality and Social Transformation, materializing, in this case, in the commitment of Gender Equality, being sure, from our ...
Carmen Martínez Perza
doaj  

Análisis de la asociación entre el fibrinógeno sérico y la severidad de la colitis ulcerosa crónica idiopática: relevancia clínica

open access: yesRevista de Cirugía Colorrectal
Objetivo: La colitis ulcerosa crónica idiopática (CUCI) se caracteriza por la inflamación de la mucosa colónica con periodos intermitentes de remisión y exacerbación de los síntomas. Se ha observado que el fibrinógeno desempeña un papel proinflamatorio en la CUCI y se ha sugerido como un posible biomarcador para detectar la actividad de la enfermedad ...
Alejandro Vela-Torres   +7 more
openaire   +2 more sources

Collaborating with transnational families: Learning from the experiences of family caretakers, educators, psychologists, and spiritual leaders in Honduras

open access: yesAmerican Journal of Community Psychology, EarlyView.
Abstract This manuscript centers on the experiences of caretakers of minors in Honduran transnational families (TNFs) in which one or both parents emigrated, and of the schoolteachers, professional psychologists, and spiritual leaders working with these families.
Marco Gemignani   +2 more
wiley   +1 more source

MAÃZ EN ASOCIACIÓN Y ROTACIÓN CON FABÃCEAS EN SUELOS ÃCIDOS DE LA SABANA DE HUIMANGUILLO, TABASCO, MEXICO

open access: yesTropical and Subtropical Agroecosystems, 2012
La asociación de cultivos es una alternativa para mejorar la fertilidad de los suelos ácidos del trópico húmedo. El objetivo de este trabajo fue evaluar el comportamiento del maíz (Zea mays L.) cultivado en asociación y rotación con fabáceas en suelos ácidos de sabana.
Samuel Córdova Sánchez   +5 more
openaire   +1 more source

Sustainable Development, Environmental Certification and the Financial Performance of the Road Passenger Transportation Sector

open access: yesCorporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Within the framework of sustainable development and environmental policy, environmental certification is regarded as a mechanism through which road passenger transport companies (RPTCs) could mitigate their adverse environmental impacts and attain competitive advantages that may enhance their financial performance.
Jose Antonio Cavero‐Rubio   +1 more
wiley   +1 more source

Vegetative growth of raspberry (Rubus idaeus L.) ‘Autumn Bliss’ with vermicompost application intercropped with lupine (Lupinus mutabilis Sweet.)

open access: yesRevista Peruana de Biología, 2013
The present investigation was carried out with objective to determine the response of red raspberry to vermicompost application and lupine (intercropped or not) in the phase of vegetative growth under greenhouse conditions in Montecillo, Mexico.
Enoc Jara-Peña   +5 more
doaj   +1 more source

Lived Experiences of Returning to Participation After Mild Stroke: A Phenomenological Study in Spain. [PDF]

open access: yesHealth Expect
ABSTRACT Introduction The process of returning to participation after a stroke depends on various individual and contextual factors, yet little is known about those with slight dependency. This study aimed to explore the experiences of people with mild sequelae after stroke in relation to their return to participation, considering the socio‐cultural ...
de Diego-Alonso C   +4 more
europepmc   +2 more sources

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