Results 161 to 170 of about 174,886 (213)

Investigating acoustic startle priming-induced cortical network reorganization in post-stroke dysarthria: a fNIRS study. [PDF]

Biomed Opt Express
Wang M, Li D, Peng C, Chen Z, Chen Y, Huang W, Lou W, Lu M, Xia N.   +8 more
europepmc   +1 more source

Metabolic feature profiling and metabolic vulnerability in acute lymphoblastic leukemia

Interdisciplinary Medicine, EarlyView.
For the first time, our study develops a novel metabolic classification and subtyping program, metabolic reprogramming‐based classifier for acute lymphoblastic leukemia, using internal PDT‐ALL‐2016 and external cohorts, which dissects metabolic profiling, clinical outcome, and therapeutic vulnerability for precision metabolic intervention in ALL ...
Xiaojie Liang, Zihong Cai, Bingqing Tang, Zicong Huang, Baiwei Luo, Bingyu Lin, Yunong Yang, Zhihao Jin, Xiaoqing Li, Xiuli Xu, Yeling Deng, Chaoran Lin, Liang Wang, Hongsheng Zhou   +13 more
wiley   +1 more source

Evaluating the effects of antimicrobial stewardship program on antimicrobial consumption and resistance patterns: a quasi-experimental study. [PDF]

BMC Infect Dis
Morsi N, Mosaad E, Ahmed O.
europepmc   +1 more source

Bioinorganic Site‐Specific Conjugation of Multi‐Arm Linkers to Create Pharmaceuticals With Targeting and Effector Functions

Journal of the Chinese Chemical Society, EarlyView.
This Account showcases a modular, multi‐arm linker platform that decouples payload loading from antibody conjugation. By leveraging a computationally designed ACPGHA zinc‐binding motif, we demonstrate the construction of homogeneous antibody‐drug conjugates and theranostic antibody‐radionuclide conjugates with high payload loading. The multi‐arm linker
Cédric Grauffel, Tse Wen Chang, Carmay Lim   +2 more
wiley   +1 more source

Explainable deep learning-based lung cancer diagnosis using clinically-guided local interpretable model-agnostic explanations. [PDF]

Sci Rep
Hassan SU, Abdulkadir SJ, Alhussian HS, Fayyaz AM, Al-Selwi SM, Khan U, Ismail AOA.   +6 more
europepmc   +1 more source

Experiencing 50 Years of Synergistic Development in Structural Biology and Enzymology

Journal of the Chinese Chemical Society, EarlyView.
Picture of Sunney Chan with Academia Sinica (AS) President James C. Liao and three Vice Presidents: Shin‐Kun Peng (left one), Tang K. Tang (right one), and Mei‐Yin Chou (right 2), taken at the annual Chinese New Year's Banquet of AS, February 7, 2025. This was likely Sunney's last appearance in formal activities of AS.
Ming‐Daw Tsai
wiley   +1 more source

The Gene Encoding the Antisense Protein ASP of HIV-1: Origin, Distribution and Maintenance. [PDF]

Viruses
Houmey MA, Sadek S, Daussy CF, Chazal N.
europepmc   +1 more source

Binuclear Copper‐Dependent Oxidative Enzymes Involved in Fungal Natural Product Modifications

Journal of the Chinese Chemical Society, EarlyView.
This article summarizes recent biochemical characterizations of a new enzyme family named by the authors as binuclear copper‐dependent oxidative enzymes (BiNCOs). Found in fungal natural product biosynthesis, BiNCOs catalyze diverse CH functionalization reactions, including C(sp3)H halogenation, C(sp3)H hydroxylation, C(sp3)O macrocyclization, and ...
Chen‐Yu Chiang, Masao Ohashi, Yi Tang
wiley   +1 more source

Brain-derived microvesicles induce activation of aspirin-treated platelets via the PLC/PKC pathway. [PDF]

Sci Rep
He YF, Zhang JC, Wang YZ, Li XC, Zhao RT, Gou YD, Yuan HJ, Tian Y.   +7 more
europepmc   +1 more source

Bridging New Programs From Concept to Rapid Development and Implementation

Journal of Dental Education, EarlyView.
ABSTRACT Through the ADEA Council of Deans Fellowship Capstone project, a new International Dentist Educational Program (IDEP) emerges as a unique program to provide educational pathways for international dentists. IDEPs expand the US dental workforce by integrating internationally trained dentists into Commission on Dental Accreditation (CODA ...
María A. Loza‐Herrero, John N. Williams, John A. Valenza   +2 more
wiley   +1 more source