Results 91 to 100 of about 12,489,349 (302)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Communication in French Foreign Language Learning by Implementing the Aspects of Interculturality

open access: yesCommunications, 2017
This research paper examines the case study and the weak sides of the implementation of intercultural education in a FLT class, and then examines how such teaching could be effective.
Jana Birova   +2 more
doaj   +1 more source

Ethical Aspects of Insurance [PDF]

open access: yes, 1972
The nature and ethical basis for insurance in general will be briefly discussed. Reference will then be made to alternatives to insurance as a means for meeting the cost of medical care.
Buckley, Louis F.
core   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

The Semantics Relation of Japanese Aspect -teiru and Negation

open access: yesArbitrer
Verb aspects in the form of -teiru in Japanese is a category that is still common to be discussed as the result of meaning classification that is prompted.
Dini Maulia, Tatang Hariri, Sailal Arimi
doaj   +1 more source

Adaptive intelligence: essential aspects [PDF]

open access: yes, 2009
The article discusses essential aspects of Adaptive Intelligence. Experimental results on optimisation of global test functions by Free Search, Differential Evolution, and Particle Swarm Optimisation clarify how these methods can adapt to multi-modal ...
Penev, Kalin
core   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

open access: yesFEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang   +7 more
wiley   +1 more source

Aspects épidémiologiques de prise en charge et conséquences des abus sexuels à l’Hôpital Général de Référence de N’djili à Kinshasa/RD Congo

open access: yesRevue des Sciences de la Santé
Les violences sexuelles basées sur le genre est un réel problème de santé publique et qui a des conséquences incalculables sur les survivantes. Cet article vise à décrire les aspects épidémiologiques et de prise en charge des abus sexuels à l’Hôpital ...
Emmanuel BOMBA DI MASUANGI   +7 more
doaj   +1 more source

Home - About - Disclaimer - Privacy