Results 91 to 100 of about 12,621,937 (301)
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
The Semantics Relation of Japanese Aspect -teiru and Negation
ArbitrerVerb aspects in the form of -teiru in Japanese is a category that is still common to be discussed as the result of meaning classification that is prompted.
Dini Maulia, Tatang Hariri, Sailal Arimi
doaj +1 more source
Communication in French Foreign Language Learning by Implementing the Aspects of Interculturality
Communications, 2017 This research paper examines the case study and the weak sides of the implementation of intercultural education in a FLT class, and then examines how such teaching could be effective.
Jana Birova +2 more
doaj +1 more source
HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
FEBS Open Bio, EarlyView.Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
Revue des Sciences de la SantéLes violences sexuelles basées sur le genre est un réel problème de santé publique et qui a des conséquences incalculables sur les survivantes. Cet article vise à décrire les aspects épidémiologiques et de prise en charge des abus sexuels à l’Hôpital ...
Emmanuel BOMBA DI MASUANGI +7 more
doaj +1 more source
FEBS Open Bio, EarlyView.A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
Evaluation of Morphometric Factors on the Distribution of Debris: A Case Study on the Attica Ripples on the South of Paveh- Kermanshah Province, Iran [PDF]
جغرافیا و پایداری محیط, 2018 Scree slopes are the evidence of rock behavior against the fluctuations of temperature and humidity.The goal is to determine the contribution of geomorphologic and solar radiation factors to the distribution of destructive evidence.
Mohammad Ahmadi
doaj
Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells
FEBS Open Bio, EarlyView.UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca +6 more
wiley +1 more source