Results 151 to 160 of about 85,975 (280)

Secoisolariciresinol Diglucoside Alleviates LPS‐Induced Acute Lung Injury by Inhibiting the NF‐κB/NLRP3 Signaling Pathway

open access: yesDrug Development Research, Volume 87, Issue 3, May 2026.
ABSTRACT Acute lung injury (ALI) and its more severe form, acute respiratory distress syndrome (ARDS), are life‐threatening pulmonary disorders with high mortality rates, and effective treatments are currently lacking. Secoisolariciresinol diglucoside (SDG), a plant lignan derived from flaxseed, possesses anti‐inflammatory and antioxidative activities.
Yuanyuan Zhong   +8 more
wiley   +1 more source

Time to Death and Predictors of Mortality in Neonates Admitted to Tibebe Ghion Referral Hospital, Neonatal Intensive Care Unit in Northwest Ethiopia: A Retrospective Follow‐Up Study

open access: yesHealth Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background and Aims The first 28 days of life, the neonatal period, represent a phase of heightened vulnerability for infant survival globally. Despite advancements in medical interventions and increased healthcare access, a substantial number of newborns continue to succumb to preventable causes annually.
Gebiyaw Wudie Tsegaye   +2 more
wiley   +1 more source

Influence of advanced maternal age (≥35 years) on maternal and neonatal outcomes in vaginally intended breech deliveries at term—A FRABAT study

open access: yesInternational Journal of Gynecology &Obstetrics, Volume 173, Issue 2, Page 889-896, May 2026.
Abstract Objective To examine maternal and neonatal outcomes in women aged 35 years and older compared with those under 35 years following planned vaginal breech deliveries. Methods This study encompassed all vaginally intended breech deliveries at the Department of Obstetrics and Perinatal Medicine at Goethe University Hospital in Frankfurt from ...
Bilal Alemi   +8 more
wiley   +1 more source

Identification of a Novel De Novo Heterozygous SEC61A1 Variant in a Patient With Severe Congenital Neutropenia

open access: yesMolecular Genetics &Genomic Medicine, Volume 14, Issue 5, May 2026.
Severe congenital neutropenia can be caused by rare SEC61A1 variants. We report a child with SCN showing granulocytic maturation arrest and abnormal immunophenotype, carrying a novel de novo SEC61A1 p.Trp379Arg variant, expanding the phenotypic and genetic spectrum of SEC61A1‐associated SCN.
Zixuan Wang   +4 more
wiley   +1 more source

Cerebral Hemodynamic Changes During Cardiac Surgery: A Feasibility MR Study in Piglets

open access: yesNMR in Biomedicine, Volume 39, Issue 5, May 2026.
Congenital heart disease surgery in infants requires cardiopulmonary bypass (CPB), which increases the risk of brain injury. Conventional heart‐lung machines (HLMs) cannot operate inside MRI scanners, limiting real‐time assessment of cerebral changes. We developed an MR‐conditional HLM and tested it in piglets during CPB.
Dominik T. Schulte   +13 more
wiley   +1 more source

Pathways to enhancing prenatal diagnosis of skeletal dysplasias

open access: yesPregnancy, Volume 2, Issue 3, May 2026.
Abstract Skeletal dysplasias are a group of Mendelian disorders that variably alter the development of the musculoskeletal system and phenotypically range from mild short stature syndromes to severe perinatal or neonatal morbidity. Prenatal diagnosis of these conditions can be challenging due to the lack of precision with ultrasound imaging compared to
Michelle Joy Wang   +4 more
wiley   +1 more source

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