Results 41 to 50 of about 44,507 (228)

An Opportunity for Cognitive Task Analysis in Neonatal Resuscitation

Frontiers in Pediatrics, 2019
Approximately 10% of newborn infants require resuscitative intervention at birth. Ideally, this care is provided by a team of expert healthcare professionals who possess exceptional cognitive, psychomotor, and communication skills.
Emily C. Zehnder, Emily C. Zehnder, Brenda H. Y. Law, Brenda H. Y. Law, Georg M. Schmölzer, Georg M. Schmölzer   +5 more
doaj   +1 more source

SUDEP and mortality in developmental and epileptic encephalopathies: A meta‐analysis of randomized clinical trials and extension studies

Epilepsia, EarlyView.
Abstract Objective Developmental and epileptic encephalopathies (DEEs) are associated with high premature mortality and increased risk of sudden unexpected death in epilepsy (SUDEP). However, epidemiological data remain limited, particularly for specific syndromes such as Dravet syndrome (DS), Lennox–Gastaut syndrome (LGS), and infantile epileptic ...
Pierludovico Moro, Maria Sole Borioni, Adolfo Mazzeo, Enrico Cocchi, Carlo Di Bonaventura, Emanuele Cerulli Irelli   +5 more
wiley   +1 more source

Return of Spontaneous Circulation Depends on Cardiac Rhythm During Neonatal Cardiac Arrest in Asphyxiated Newborn Animals

Frontiers in Pediatrics, 2021
Objective: Pulseless electrical activity (PEA) occurs in asphyxiated newborn piglets and infants. We aimed to examine whether different cardiac rhythms (asystole, bradycardia, PEA) affects the resuscitation outcomes during continuous chest compressions ...
Michael Wagner, Michael Wagner, Po-Yin Cheung, Po-Yin Cheung, Maryna Yaskina, Tze-Fun Lee, Vanessa A. Vieth, Megan O'Reilly, Megan O'Reilly, Georg M. Schmölzer, Georg M. Schmölzer, Georg M. Schmölzer   +11 more
doaj   +1 more source

Astrocyte subtype‐specific alterations in the dentate gyrus of individuals with mesial temporal lobe epilepsy

Epilepsia Open, EarlyView.
Abstract Objective Epilepsy affects approximately 50 million people worldwide and, although primarily attributed to neuronal dysfunction, increasing evidence highlights a critical role of glial cells, particularly astrocytes, in the pathophysiological mechanisms.
Chiara Lötzsch, Jakob Johann Schmidt, Daniel Delev, Roland Coras, Ingmar Blümcke, Ruth Beckervordersandforth   +5 more
wiley   +1 more source

A smart mattress for detecting and correcting the prone position: A feasibility study toward night‐time SUDEP prevention

Epilepsia Open, EarlyView.
Abstract Objective Sudden unexpected death in epilepsy (SUDEP) is the leading cause of death in otherwise healthy patients with epilepsy; about 70% occurs during sleep, and nearly 90% of patients are found prone (face‐down). Following a nocturnal seizure, terminal apnea occurs between 2.5 and 10.8 min postictally (median ~ 5 min), defining a narrow but
Jong Woo Lee, Pranav Bansal, Ioannis Smanis, Justin Nguyen, Ellen Pritchard, Janet Orozco, Andres Rodriguez   +6 more
wiley   +1 more source

Effects of Intramuscular Vasopressin on Pharmacokinetics and Pharmacodynamics in Healthy Neonatal Piglets: A Dose–Response Study

Children
Background: Neonatal resuscitation guidelines recommend the use of the vasopressor epinephrine during neonatal cardiopulmonary resuscitation (CPR); however, vasopressin may be a potential alternative.
Marwa Ramsie, Po-Yin Cheung, Raza Hyderi, Shrieya Praveen, Tze-Fun Lee, Megan O’Reilly, Georg M. Schmölzer   +6 more
doaj   +1 more source

Evaluating predictive values of umbilical cord arterial lactate for adverse newborn outcomes among term‐births in northern Uganda: A cross sectional analytical study

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 408-420, April 2025.
Abstract Objective Birth asphyxia is one of the leading causes of death for neonates worldwide. Lack of an objective cost effective test to predict poor newborn outcomes at birth affects the ability to respond appropriately. This study determined predictive values of umbilical cord arterial lactate in relation to adverse neonatal outcomes. Methods This
Elizabeth Ayebare, James K. Tumwine, Jolly Nankunda, Anna Hjelmstedt, Wibke Jonas, Grace Ndeezi, Nicola Orsini, Claudia Hanson   +7 more
wiley   +1 more source

Reducing Brain Injury of Preterm Infants in the Delivery Room

Frontiers in Pediatrics, 2018
Cerebrovascular injury is one of the major detrimental consequences of preterm birth. Recent studies have focused their attention on factors that contribute to the development of brain lesions immediately after birth. Among those factors, hypothermia and
Francesca Viaroli, Francesca Viaroli, Po-Yin Cheung, Po-Yin Cheung, Megan O'Reilly, Megan O'Reilly, Graeme R. Polglase, Gerhard Pichler, Georg M. Schmölzer, Georg M. Schmölzer   +9 more
doaj   +1 more source

Doppler Ultrasound for Heart Rate Assessment in a Porcine Model of Neonatal Asphyxia

Frontiers in Pediatrics, 2020
Objectives: Approximately 10% of newborn infants require resuscitation at birth. Accurate heart rate (HR) assessment guides resuscitation interventions, thereby reducing morbidities and mortality.
Nicolò Morina, Nicolò Morina, Peter A. Johnson, Peter A. Johnson, Peter A. Johnson, Megan O'Reilly, Megan O'Reilly, Tze-Fun Lee, Tze-Fun Lee, Maryna Yaskina, Po-Yin Cheung, Po-Yin Cheung, Georg M. Schmölzer, Georg M. Schmölzer   +13 more
doaj   +1 more source

Comparison of Cranial Ultrasound and Amplitude‐Integrated Electroencephalography in Predicting Neurodevelopmental Outcomes in Neonates With Hypoxic–Ischemic Encephalopathy: A Systematic Review and Meta‐Analysis

Journal of Clinical Ultrasound, EarlyView.
In neonates with hypoxic–ischemic encephalopathy (HIE), adverse neurodevelopmental outcomes (NDO) remain common. Amplitude‐integrated EEG demonstrates strong prognostic value for early prediction, while cranial ultrasound (cUS) provides complementary but less definitive information.
Meirong Shu, Shilue Zhong, Bo Bao, Dandan Xu, Yingfeng Jiang, Dongxue Lin, Jingzhi Su   +6 more
wiley   +1 more source