Results 11 to 20 of about 3,567 (207)

Neonatal tetanus [PDF]

Pediatric Emergency Medicine Journal, 2021
Neonatal tetanus, also known as tetanus neonatorum, occurs in young infants of inadequately immunized mothers. It is a kind of generalized tetanus that is exhibited mainly by prevention of the release of the inhibitory neurotransmitters (i.e ...
Itzhak Brook
doaj   +1 more source

Pemphigus and pemphigoids: Clinical presentation, diagnosis and therapy

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 21, Issue 10, Page 1188-1209, October 2023., 2023
Summary Pemphigus and pemphigoid are two potentially life‐threatening groups of autoimmune diseases, characterized by autoantibodies targeting structural components of desmosomes or hemidesmosomes, respectively. Affected patients typically show itchy/painful plaques or blistering skin lesions and/or impairing mucosal blistering and erosions, which may ...
Dario Didona, Morna F. Schmidt, Roberto Maglie, Farzan Solimani   +3 more
wiley   +1 more source

Whole‐exome sequencing identified five novel de novo variants in patients with unexplained intellectual disability

Journal of Clinical Laboratory Analysis, Volume 36, Issue 9, September 2022., 2022
Briefly, we identified five novel de novo variants in four known genes associated with intellectual disability, namely COL4A1 (c.2786 T>A,p.V929D, and c.2797G>A, p.G933S), TBR1 (c.1639_1640insCCCGCAGTCC, p.Y553Sfs*124), CHD7 (c.7013A>T, p.Q2338L), and TUBA1A (c.1350del, p.E450Dfs*34).
Wenqiu Zhang, Li Hu, Xinyi Huang, Dan Xie, Jiangfen Wu, Xiaoling Fu, Daiyi Liang, Shengwen Huang   +7 more
wiley   +1 more source

Efficacy of melatonin in term neonatal models of perinatal hypoxia‐ischaemia

Annals of Clinical and Translational Neurology, Volume 9, Issue 6, Page 795-809, June 2022., 2022
Abstract Objective Neonatal encephalopathy (NE) is an important cause of mortality and disability worldwide. Therapeutic hypothermia (HT) is an effective therapy, however not all babies benefit. Novel agents are urgently needed to improve outcomes. Melatonin in preclinical studies has promising neuroprotective properties.
Raymand Pang, Hyun Jee Han, Christopher Meehan, Xavier Golay, Suzanne L. Miller, Nicola J. Robertson   +5 more
wiley   +1 more source

High-risk factors for adverse pregnancy outcomes in systemic lupus erythaematosus: a retrospective study of a Chinese population

BMJ Open, 2021
Objective To clarify high-risk factors for adverse pregnancy outcomes (APOs) in systemic lupus erythaematosus (SLE).Design A retrospective chart review study.Setting Data were collected in a tertiary medical centre, Shanghai, China, from November 2010 to
Jiayue Wu, Wen Di, Qiong Fu, Meng Jiang, You Wang, Yanling Chang, Sihan Lin   +6 more
doaj   +1 more source

Subcutaneous fat necrosis of the newborn – An atypical case with typical complications

Clinical Case Reports, Volume 9, Issue 4, Page 2069-2073, April 2021., 2021
Subcutaneous fat necrosis of the newborn should be considered in newborns with suggestive skin lesions, even in the absence of perinatal distress. SCFN may cause long‐standing complications, like hypertriglyceridemia or hypercalcemia. Hypercalcemia can be refractory to therapy and lead to poor weight gain and nephrocalcinosis, which should be closely ...
Cristina Lorenzo, Andreia Romana, Joana Matias, Paulo Calhau   +3 more
wiley   +1 more source

The performance of the alarmin HMGB1 in pediatric diseases: From lab to clinic

Immunity, Inflammation and Disease, Volume 9, Issue 1, Page 8-30, March 2021., 2021
Abstract Introduction The ubiquitously expressed nonhistone nuclear protein high‐mobility group box protein 1 (HMGB1) has different functions related to posttranslational modifications and cellular localization. In the nucleus, HMGB1 modulates gene transcription, replication and DNA repair as well as determines chromosomal architecture.
Bo Li, Xin Peng, He Li, Fei Chen, Yuxia Chen, Yingqian Zhang, Kai Le   +6 more
wiley   +1 more source

[Retracted] Early Physical Linear Growth of Small‐for‐Gestational‐Age Infants Based on Computer Analysis Method

Journal of Healthcare Engineering, Volume 2021, Issue 1, 2021., 2021
This article proposes that machine learning can break through the technical limitations of the linear growth test for the early physique of infants smaller than gestational age and can accurately calculate and predict the consequences of the disease. For testing the linear growth of the early physique of infants smaller than gestational age, the data ...
Li Ruixiang, Yin Mingrong, Cui Li, Zheng Rongxiu, Malik Alazzam   +4 more
wiley   +1 more source

[Retracted] Clinical Observation of Effects of Prepregnancy Body Mass Index and Weight Gain during Pregnancy on Neonatal Weight and Delivery Outcome

Evidence-Based Complementary and Alternative Medicine, Volume 2021, Issue 1, 2021., 2021
Objective. The increase of BMI before pregnancy and during pregnancy will lead to hypertensive disorder in pregnancy (HDP) and abnormal glycolipid metabolism, as well as increase the risk of neonatal weight abnormalities and adverse pregnancy outcome. This study retrospectively analyzed the clinical data of 358 women who were admitted to the obstetrics
Yan Jin, Xiwang Dai, Nan Wang, Yaowei Hu, Limei Quan, Shuli Zhu, Songwen Tan   +6 more
wiley   +1 more source

Cardiac troponin as biochemical marker of perinatal asphyxia and hypoxic myocardial injury [PDF]

Vojnosanitetski Pregled, 2009
Background/Aim. Myocardial cell lesion in newborns may be clinically occult. In recent years there has been shown growing interest in the use of cardiac troponin-I (cTnI) in relation to perinatal asphyxia and hypoxic myocardial lesion.
Simović Aleksandra M., Knežević Jasmina, Igrutinović Zoran, Stojanović Nadežda, Kocić Sanja   +4 more
doaj   +1 more source