Evolution and diversification of carboxylesterase-like [4+2] cyclases in aspidosperma and iboga alkaloid biosynthesis. [PDF]
Proc Natl Acad Sci U S A, 2023 Monoterpene indole alkaloids (MIAs) are a large and diverse class of plant natural products, and their biosynthetic construction has been a subject of intensive study for many years.
DeMars MD, O'Connor SE.
europepmc +2 more sources
Estudos em Aspidosperma Mart. & Zucc. (Apocynaceae): Integrando morfologia e filogenia [PDF]
HoehneaRESUMO Um dos gêneros mais importantes de Apocynaceae, Aspidosperma apresenta desafios na delimitação de espécies devido à sobreposição de caracteres morfológicos e o grande número de sinonímias.
Carlos Alexandre dos Santos Teixeira +3 more
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Aspidosperma nitidum reduces parasite load and modulates cytokines in BALB/c mice infected with Leishmania (Leishmania) amazonensis. [PDF]
Front ChemThe lack of vaccines shows the need for alternative leishmaniasis treatments. In vitro study previously demonstrated the leishmanicidal activity of A. nitidum extracts. This study describes for the first time, the antileishmanial activity of A.
Brígido HPC +11 more
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Recycling Upstream Redox Enzymes Expands the Regioselectivity of Cycloaddition in Pseudo-Aspidosperma Alkaloid Biosynthesis. [PDF]
J Am Chem Soc, 2022 Nature uses cycloaddition reactions to generate complex natural product scaffolds. Dehydrosecodine is a highly reactive biosynthetic intermediate that undergoes cycloaddition to generate several alkaloid scaffolds that are the precursors to ...
Kamileen MO +8 more
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A natural small molecule aspidosperma-type alkaloid, hecubine, as a new TREM2 activator for alleviating lipopolysaccharide-induced neuroinflammation in vitro and in vivo. [PDF]
Redox BiolNeuroinflammation and oxidative stress play a crucial role in the pathogenesis of neurodegenerative diseases, including Alzheimer’s disease. The triggering receptor expressed on myeloid cells 2 (TREM2), highly expressed by microglia in the central ...
Li L +6 more
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Angewandte Chemie, 2023 We report here a homo-Mannich reaction of cyclopropanol with iminium ion generated by an asymmetric allylic dearomatization of indole to construct a tricyclic hydrocarbazole core, which is shared by a variety of monoterpenoid indole alkaloids across ...
D. Jiang +8 more
semanticscholar +1 more source
Bonplandia, 2020 Aspidosperma quirandy Hassl. is reestablished as a different taxon from Aspidosperma tomentosum Mart. Updated descriptions from both taxa, an identification key, ecological observations and new reference material are presented.
Juana De Egea Elsam +3 more
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Variação fenotípica para caracteres silviculturais em populações de Aspidosperma spp. sem estrutura de progênies. Genetic variation for silvicultural traits in populations of Aspidosperma spp. without progeny arrays. [PDF]
Revista do Instituto Florestal, 2016 O objetivo deste estudo foi estimar os parâmetros genéticos para os caracteres silviculturais em Aspidosperma polyneuron Müll.Arg. e Aspidosperma cylindrocarpon Müll.Arg., para fins de conservação ex situ e uso em programas de recuperação ambiental. A
Camila Regina Silva Baleroni RECCO +7 more
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Water, 2023 Chemically modified bioadsorbents were prepared using sawdust (Aspidosperma polyneuron) functionalized with urea at different concentrations (BC-1M, BC-3M, and BC-6M) to evaluate their adsorption capacity by the methylene blue method.
R. Ortega-Toro +4 more
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Anales del Jardín Botánico de Madrid, 2006 Mandevilla nevadana, a new species endemic to the Sierra Nevada de Santa Marta, Colombia, is described and illustrated. Allomarkgrafia ecuatoriana, Aspidosperma capitatum, and Prestonia mexicana are reported for the first time in Colombia.
Juan Francisco Morales
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