Results 61 to 70 of about 303,717 (266)
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
TASTE: To aspirate, or not to aspirate, remains a question
Global Cardiology Science and Practice, 2014 Coronary artery thrombus aspiration is a simple, rapidly performed, and relatively inexpensive adjunctive therapy in primary percutaneous coronary intervention (PCI). It may protect the microcirculation from distal embolization and improve distal coronary blood flow, although this is not a universal finding.
openaire +2 more sources
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Fir branch as rare cause of aspiration pneumonia in adults
Бюллетень сибирской медицины, 2018 The article represents a clinical observation describing the case of mechanical obstruction in the respiratory passages with an unusual foreign body, a fir branch.
S. N. Kosarev +6 more
doaj +1 more source
It Takes a Village: Listening to Parents
Education Sciences, 2020 The study was premised on the concern of the migrant African parents about their children’s lack of aspiration for higher education after completing their secondary education in the Northern Territory (NT), Australia.
Stephen Bolaji +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Effect of a Single Dose of Metoclopramide on Gastric Volume in Fasting Diabetic Patients Measured using Ultrasonography: A Randomised Controlled Trial [PDF]
Journal of Clinical and Diagnostic ResearchIntroduction: Diabetic patients have delayed gastric emptying time and even if adequately fasted before elective surgery, are found to have increased Gastric Volume (GV) compared to non diabetic patients. Increased GV poses them with an increased risk of
Shwetha K Mudalagirigowda +2 more
doaj +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source