Results 351 to 360 of about 447,619 (420)

Errors in Abstract and Methods.

JAMA Netw Open
europepmc   +1 more source

Effectiveness of aspirin in preventing deep vein thrombosis following proximal femoral fracture surgery in Japan. [PDF]

Sci Rep
Ohmori T, Toda K, Taoka T, Ishihara T, Ito Y.   +4 more
europepmc   +1 more source

Clonal Hematopoiesis and Thrombosis

American Journal of Hematology, EarlyView.
ABSTRACT Clonal hematopoiesis (CH) has been the focus of many research efforts in the last years and has emerged as a risk modifier for cardiovascular disease morbidity and mortality. While substantial evidence has accumulated regarding its impact on arterial system diseases, the connection with venous thrombosis has only recently been explored.
Cornelia Englisch, Cihan Ay
wiley   +1 more source

Targeting Arachidonic Acid Metabolism Enhances Immunotherapy Efficacy in ARID1A-Deficient Colorectal Cancer. [PDF]

Cancer Res
Cui L, Liu R, Han S, Zhang C, Wang B, Ruan Y, Yu X, Li Y, Yao Y, Guan X, Liao Y, Su D, Ma Y, Li S, Liu C, Zhang Y.   +15 more
europepmc   +1 more source

Functional Characterization of a Genetic Variant in the 5′ UTR of APC 1B Promoter in a Familial Adenomatous Polyposis Family

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Pathogenic germline variants in the APC gene result in familial adenomatous polyposis (FAP) which can escalate into colon cancer. Standard clinical testing failed to identify pathogenic variants in a 4‐generation FAP family. We identified and assessed co‐segregation of a 5′ untranslated region (UTR) variant, NM_001127511.3 (APC) c.‐40G>A ...
Brendon Young, Deborah W. Neklason, Kathleen Clark, Bing‐Jian Feng, Megan B. Keener, Thérèse M. Tuohy, Austin Wood, Wendy C. McKinnon, Marc S. Greenblatt, Sean V. Tavtigian   +9 more
wiley   +1 more source

Formative research to optimize pre-eclampsia risk-screening and prevention (PEARLS): study protocol. [PDF]

Reprod Health
Minckas N, Swarray-Deen A, Fawcus S, Ndiema RC, McDougall A, Scott J, Oppong SA, Osman A, Osoti AO, Eddy K, Matjila M, Gwako GN, Vogel JP, Gülmezoglu AMA, Nwameme AU, Bohren MA, PEARLS Trial collaborative group.   +16 more
europepmc   +1 more source

Costello Syndrome and Ophthalmologic Issues: Unveiling the Unseen

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Costello syndrome (CS) is an ultra‐rare condition belonging to the RASopathies, a group of disorders characterized by aberrant RAS/MAPK pathway signaling, which is involved in ocular development and in some eye pathologies. However, only a few studies assessing the ophthalmic features of individuals with CS are available.
Sofia Peschiaroli, Germana Viscogliosi, Annabella Salerni, Emanuele Crincoli, Roberta Mattei, Tommaso Verdolotti, Serafina Antonella Loprete, Valentina Trevisan, Giovanni Antonio Marrocco, Alessia Cherubino, Lucrezia Perri, Roberta Onesimo, Giuseppe Zampino, Chiara Leoni   +13 more
wiley   +1 more source

The impact of aspirin combined with labetalol on coagulation function and pregnancy outcomes in pre-eclamptic pregnant women. [PDF]

BMC Pregnancy Childbirth
Zhang M, Ren X, Song D.
europepmc   +1 more source

Genomics Review of Selective RET Inhibitors Sensitivity in Thyroid Cancer Clinical Trials

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT RET gene is a driver of thyroid cancer (TC) tumorigenesis. The incidence of TC has increased worldwide in the last few decades, both in medullary and follicular‐derived subtypes. Several drugs, including multikinase and selective inhibitors, have been explored.
Sara Gil‐Bernabé, Lucía García‐DeLaFuente, Alejandro García‐Álvarez, Ginesa García‐Rostán, Jaume Capdevila, Jorge Hernando   +5 more
wiley   +1 more source

Polygenic risk, aspirin, and primary prevention of coronary artery disease. [PDF]

Eur Heart J Cardiovasc Pharmacother
Yu C, Natarajan P, Patel AP, Bhatia HS, Khera AV, Neumann JT, Tsimikas S, Wolfe R, Nicholls SJ, Reid CM, Zoungas S, Tonkin AM, McNeil JJ, Lacaze P.   +13 more
europepmc   +1 more source