Results 91 to 100 of about 44,631 (306)
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Development of human monoclonal antibodies against TARM1 by yeast display
FEBS Open Bio, EarlyView.Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source
Neotropical Ichthyology, 2019 Morphological characters of species are essential for assessing the functional structure of a fish assemblage, since differences between them, for example in body shape, are related to many functional and ecological traits (e.g., swimming, search for ...
Carolina C. Siliprandi +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
Fish assemblage structure in the Chishui River, a protected tributary of the Yangtze River
, 2011 This study aimed to characterize fish assemblage and evaluate environmental influence on fish distribution in the Chishui River, a protected tributary of the upper Yangtze River.
Cao, W. +5 more
core
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
Periphytic diatoms as bioindicators in a tropical stream: from urban to rural environments
Acta Scientiarum: Biological Sciences, 2015 Urbanization and agriculture alter expressively the physical and chemical variables of lotic habitats, especially streams, causing negative effects to the biota of these environments.
Carina Moresco +2 more
doaj +1 more source
, 2015 Changes in land cover and fish assemblage structure were assessed across two spatial and temporal scales in the Piedmont and Coastal Plain regions of the Chesapeake Bay watershed in Virginia.
Stickley, Samuel F
core +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Ecología Austral, 2018 We selected streams located in north-eastern Brazil with the objective of assessing the effect of streams of different orders (1st, 2nd, 3rd) on the distribution and composition of benthic macroinvertebrates in the rainy and dry seasons.
Jessica F. Gomes Pio +3 more
doaj +1 more source