Results 31 to 40 of about 634,315 (303)

Assessing the Corporate Governance Framework of Local Governments in Ghana [PDF]

open access: yesInternational Journal of Management, Accounting and Economics
International best practices require that corporate governance principles are introduced to guide institutions to operate in the best interest of stakeholders.
Anthony Aikins, David Essaw, John Mensah
doaj   +1 more source

Mechanistic principles of an ultra-long bovine CDR reveal strategies for antibody design

open access: yesNature Communications, 2021
Certain bovine antibodies have ultra-long long complementarity-determining regions (CDRs) that contain a knob for antigen interaction, which is connected to the antibody through a stalk.
Hristo L. Svilenov   +4 more
doaj   +1 more source

BIGMAC : breaking inaccurate genomes and merging assembled contigs for long read metagenomic assembly. [PDF]

open access: yes, 2016
BackgroundThe problem of de-novo assembly for metagenomes using only long reads is gaining attention. We study whether post-processing metagenomic assemblies with the original input long reads can result in quality improvement.
Clum, Alicia   +3 more
core   +2 more sources

Tuning gradient boosting for imbalanced bioassay modelling with custom loss functions

open access: yesJournal of Cheminformatics, 2022
While in the last years there has been a dramatic increase in the number of available bioassay datasets, many of them suffer from extremely imbalanced distribution between active and inactive compounds.
Davide Boldini   +3 more
doaj   +1 more source

The role of disorder in RNA binding affinity and specificity [PDF]

open access: yesOpen Biology, 2020
Most RNA-binding modules are small and bind few nucleotides. RNA-binding proteins typically attain the physiological specificity and affinity for their RNA targets by combining several RNA-binding modules.
Diana S. M. Ottoz, Luke E. Berchowitz
doaj   +1 more source

SIMBA: a web tool for managing bacterial genome assembly generated by Ion PGM sequencing technology [PDF]

open access: yes, 2016
Background The evolution of Next-Generation Sequencing (NGS) has considerably reduced the cost per sequenced-base, allowing a significant rise of sequencing projects, mainly in prokaryotes. However, the range of available NGS platforms requires different
Aguiar, Edgar L.   +13 more
core   +3 more sources

Networks of VTA Neurons Encode Real-Time Information about Uncertain Numbers of Actions Executed to Earn a Reward

open access: yesFrontiers in Behavioral Neuroscience, 2017
Multiple and unpredictable numbers of actions are often required to achieve a goal. In order to organize behavior and allocate effort so that optimal behavioral policies can be selected, it is necessary to continually monitor ongoing actions.
Jesse Wood   +7 more
doaj   +1 more source

Research on product classification of civil aircraft

open access: yesHangkong gongcheng jinzhan, 2023
Civil aircraft is assembled by various and a large number of parts and components, which requires a clear classification of aircraft products to establish an efficient technology control mechanism throughout the whole lifecycle.
LI Huiying, WU Hua, XIONG Jun, MENG Xu
doaj   +1 more source

Engineering heterogeneity of precision nanoparticles for biomedical delivery and therapy

open access: yesView, 2021
Nanoparticle (NP)‐based vehicles are attractive for biomedical delivery and therapy, owing to improved therapeutic efficiency and reduced adverse effects compared to free drugs.
Di Zheng, Kuikun Yang, Zhihong Nie
doaj   +1 more source

DNA functionalized plasmonic nanoassemblies as SERS sensors for environmental analysis

open access: yesAggregate, 2023
Surface‐enhanced Raman scattering (SERS) is among the most widely applied analytical techniques due to its easy execution and extreme sensitivity. Target molecules can be detected and distinguished based upon the fingerprint spectra that arise when ...
Jinxiang Li, Xueqin Chen, Jun‐Jie Zhu
doaj   +1 more source

Home - About - Disclaimer - Privacy