Results 61 to 70 of about 312,451 (313)
, 2015 This is a tarred (compressed) file that contains assemblies to an artificial reference genome. When untarred, this file will contain >800 files in .bam format, one for each individual fish. These files were produced using bwa (Burrows-Wheeler Aligner, Li
McDonald, David B. +7 more
core +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Enzyme-substrate hybrid β-sheet controls geometry and water access to the γ-secretase active site
Communications Biology, 2023 γ-Secretase is an aspartyl intramembrane protease that cleaves the amyloid precursor protein (APP) involved in Alzheimer’s disease pathology and other transmembrane proteins. Substrate-bound structures reveal a stable hybrid β-sheet immediately following
Shu-Yu Chen +4 more
doaj +1 more source
Citizens' Assemblies and Sustainability Transitions
, 2022 reservedIn recent years, Democratic Innovations (DIs) such as Citizens’ Assemblies have been given considerable attention. Partly due to successful initiatives in Europe (e.g., Irish CA and Citizens’ Convention on Climate) and partly because of climate ...
POPOV, IVAN
core
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
trinity-assemblies-for-dryad.tar.gz
, 2016 De novo Trinity (trinityrnaseq_r2013-02-25) assemblies of raw-reads for all individuals included in ...
Matthew D. McGee (3240747) +13 more
core +1 more source
q20 comparison genome assemblies
, 2022 Comparison of r9.4.1, r10.3 and r10.4 nanopore flowcell genome assemblies and hybrid Illumina/nanopore assemblies. Includes assemblies from flye, canu, unicycler and spades.
Nicole Stoesser (8381946) +1 more
core +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
pH-Responsive Properties of Asymmetric Nanopapers of Nanofibrillated Cellulose
Nanomaterials, 2020 Inspired by plant movements driven by the arrangement of cellulose, we have fabricated nanopapers of nanofibrillated cellulose (NFC) showing actuation under pH changes.
Maud Chemin +3 more
doaj +1 more source