Results 51 to 60 of about 6,464,903 (301)
Regulation of extracellular matrix assembly and structure by hybrid M1/M2 macrophages
bioRxiv, 2020 Aberrant extracellular matrix (ECM) assembly surrounding implanted biomaterials is the hallmark of the foreign body response, in which implants become encapsulated in thick fibrous tissue that prevents their proper function.
Claire E. Witherel +7 more
semanticscholar +1 more source
Molecules and Cells, 2018 A class of long noncoding RNAs (lncRNAs) has architectural functions in nuclear body construction; however, specific RNA domains dictating their architectural functions remain uninvestigated.
Tomohiro Yamazaki +9 more
semanticscholar +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Microbiome Assembly across Multiple Body Sites in Low-Birthweight Infants
mBio, 2013 The purpose of this study was to evaluate the composition and richness of bacterial communities associated with low-birthweight (LBW) infants in relation to host body site, individual, and age.
Elizabeth K. Costello +4 more
doaj +1 more source
Signals controlling Cajal body assembly and function [PDF]
The International Journal of Biochemistry & Cell Biology, 2013 Cajal bodies (CBs) are subnuclear domains that participate in the biogenesis of small nuclear ribonucleoproteins (snRNPs) and telomerase. CBs are found in cells with high splicing demands, such as neuronal and cancer cells. The purpose of this review is to highlight what is known about the signals that impact the formation and activity of CBs ...
openaire +2 more sources
P-body assembly requires DDX6 repression complexes rather than decay or Ataxin2/2L complexes
Molecular Biology of the Cell, 2015 DDX6 is an abundant DEAD-box helicase associated with various complexes involved in mRNA decay and repression. Its interactome in human cells was analyzed to identify its most prominent partners.
Jessica Ayache +6 more
semanticscholar +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
A centriolar FGR1 oncogene partner-like protein required for paraflagellar rod assembly, but not axoneme assembly in African trypanosomes [PDF]
Open Biology, 2018 Proteins of the FGR1 oncogene partner (or FOP) family are found at microtubule organizing centres (MTOCs) including, in flagellate eukaryotes, the centriole or flagellar basal body from which the axoneme extends.
Jane Harmer +5 more
doaj +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Rigid Body Assembly Impact Models for Adiabatic Cutoff Equipments
Engineering Transactions, 2014 This paper is concerned with systems consisting of components colliding with each other. In particular, a high velocity adiabatic impact cutoff machine is investigated.
M. MASSENZIO +3 more
doaj +1 more source