Results 81 to 90 of about 6,464,903 (301)

Design of CKD_6E Electric Drive Shunting Diesel Locomotive Body

机车电传动, 2019
In order to shorten the development cycle and improve the assembly efficiency of the car body, the CKD6E electric drive shunting diesel locomotive body was developed with modular technology.
Shaoyi LI, Guofu HE, Maoguang DENG, Huanxian LI, Ke LI, Ziquan PENG   +5 more
doaj  

Stable body sizes in soil nematodes across altitudes: The role of intrageneric variation in community assembly

Ecology and Evolution
Animal body size exhibits rapid responses to environmental variations and displays considerable variability across ecological scales, significantly influencing ecological community assembly. However, our understanding of the extent of body size variation
Teng Li, Xianping Li, Lingyun Zheng, Huixin Li   +3 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

The structure of basal body inner junctions from Tetrahymena revealed by electron cryo-tomography

The EMBO Journal
The cilium is a microtubule-based eukaryotic organelle critical for many cellular functions. Its assembly initiates at a basal body and continues as an axoneme that projects out of the cell to form a functional cilium.
Sam Li, Jose-Jesus Fernandez, Marisa D Ruehle, Rachel A Howard-Till, Amy Fabritius, Chad G Pearson, David A Agard, Mark E Winey   +7 more
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Electronic skins for soft, compact, reversible assembly of wirelessly activated fully soft robots

Science Robotics, 2018
A skin-like driving system enables compact and reversible assembly of wirelessly activated, fully soft robots. Designing softness into robots holds great potential for augmenting robotic compliance in dynamic, unstructured environments.
J. Byun, Yoontaek Lee, Jae-Jun Yoon, Byeongmoon Lee, Eunho Oh, Seungjun Chung, Takhee Lee, Kyu-Jin Cho, Jaeha Kim, Yongtaek Hong   +9 more
semanticscholar   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

A basal body microtubule singlet-to-doublet transition in Plasmodium male gametogenesis

Nature Communications
Axoneme assembly constitutes a pivotal process in male gametogenesis of Plasmodium. Plasmodium possesses a unique nuclear envelope-anchored basal body that templates axoneme assembly, distinct from the basal body that templates the axoneme of cilia or ...
Shuzhen Yang, Shanshan Ma, Chengxian Yuan, Zhixun Li, Fanbiao Ji, Luming Yao, Huiting Cui, Qiang Guo, Jing Yuan   +8 more
doaj   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source