Results 71 to 80 of about 942,194 (293)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

FY2012 ICN report of savings [PDF]

, 2013
Iowa Code section 8D.10 requires certain state agencies prepare an annual report to the General Assembly certifying the identified savings associated with that state agency’s use of the Iowa Communications Network (ICN).

core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Code of Medical Ethics

Zdravniški Vestnik, 2017
Te Code was approved on December 12, 1992, at the 3rd regular meeting of the General Assembly of the Medical Chamber of Slovenia and revised on April 24, 1997, at the 27th regular meeting of the General Assembly of the Medical Chamber of Slovenia.
. SZD-SZZ
doaj  

Thermal-hydraulic calculations for a fuel assembly in a European Pressurized Reactor using the RELAP5 code

Nukleonika, 2015
The main object of interest was a typical fuel assembly, which constitutes a core of the nuclear reactor. The aim of the paper is to describe the phenomena and calculate thermal-hydraulic characteristic parameters in the fuel assembly for a European ...
Skrzypek Maciej, Laskowski R.
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Using of the Serpent code based on the Monte-Carlo method for calculation of the VVER-1000 fuel assembly characteristics

Ядерна фізика та енергетика, 2016
The description of calculation scheme of fuel assembly for preparation of few-group characteristics is considered with help of Serpent code. This code uses the Monte-Carlo method and energy continuous microscopic data libraries.
V. V. Galchenko, V. I. Gulik, I. I. Shlapak   +2 more
doaj  

Thermal Hydraulic and Neutronics Coupling Analysis for Plate Type Fuel in Nuclear Reactor Core

Science and Technology of Nuclear Installations, 2020
The thermal hydraulic and neutronics coupling analysis is an important part of the high-fidelity simulation for nuclear reactor core. In this paper, a thermal hydraulic and neutronics coupling method was proposed for the plate type fuel reactor core ...
Linrong Ye, Mingjun Wang, Xin’an Wang, Jian Deng, Yan Xiang, Wenxi Tian, Suizheng Qiu, G. H. Su   +7 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Light diffusion and localization in 3D nonlinear disordered media

, 2006
Using a 3D Finite-Difference Time-Domain parallel code, we report on the linear and nonlinear propagation of light pulses in a disordered assembly of scatterers, whose spatial distribution is generated by a Molecular Dynamics code; refractive index ...
A. Taflove, C. Conti, D. S. Wiersma, G. Ruocco, L. Angelani   +4 more
core   +1 more source