Results 71 to 80 of about 6,311,624 (290)

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

open access: yesFEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli   +2 more
wiley   +1 more source

An Evolutionary Procedure for a Bi-Objective Assembly Line Balancing Problem

open access: yesMathematics
An assembly line is a manufacturing process commonly used in the production of commodity goods. The assembly process is divided into elementary tasks that are sequentially performed at serially arranged workstations.
Jordi Pereira, Mariona Vilà
doaj   +1 more source

An improved immune algorithm for simple assembly line balancing problem of type 1

open access: yesJournal of Algorithms & Computational Technology, 2017
In order to solve the simple assembly line balancing problem of type 1, an improved immune algorithm is proposed. Compared with the basic immune algorithm: (1) The similarity formula between any two antibodies is simplified in the improved immune ...
Han-ye Zhang
doaj   +1 more source

GBS‐MeDIP: A method for the simultaneous identification of genetic and epigenetic variants in tumors

open access: yesFEBS Open Bio, EarlyView.
GBS‐MeDIP combines DNA sequencing with enrichment of methylated DNA to profile genetic and epigenetic variation in the same reduced genomic fraction. Applied to gastric cancer and parathyroid tumors, it identifies sequence variants, copy number changes, and differentially methylated regions together, helping distinguish true epigenetic changes from ...
Fábio Pértille   +6 more
wiley   +1 more source

LINE BALANCING LINI PERAKITAN PRODUK TORCH LIGHT (STUDI KASUS PT ARISAMANDIRI PRATAMA)

open access: yesJ@ti Undip: Jurnal Teknik Industri, 2012
Line balancing yang baik akan meningkatkan efisiensi proses produksi. Pada lini perakitan produk torch light (lampu senter) tipe FL-R20NU2A PT. Arisamandiri Pratama waktu idle karena waktu proses di stasiun kerja yang belum seimbang kadang menyebabkan ...
Ratna Purwaningsih, Prima Hazairin
doaj   +1 more source

A Three-Stage Optimization Method for Assembly Line Balancing Problem

open access: yesIEEE Access, 2020
Considering the characteristics of multimodels production pattern on assembly line, the assembly line balancing problem which is non-deterministic polynomial hard becomes more challenging to complete. In this article, we propose a reformulation of simple
Qidong Yin, Xiaochuan Luo
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

The Comprehensive Live Cell‐Based Cytotoxicity Assay for Monitoring Disease Activity and Guiding Rescue Therapy in Acute Attacks of NMOSD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a devastating neurological disease that lacks serological biomarkers that can accurately reflect disease activity. We established a live cell‐based assay (LCBA) using serum with endogenous complement to quantify the overall cytotoxicity, offering a novel functional tool for monitoring
Xiaona Xu   +10 more
wiley   +1 more source

Balancing Problem of Stochastic Large-Scale U-Type Assembly Lines Using a Modified Evolutionary Algorithm

open access: yesIEEE Access, 2018
U-type assembly lines have become a mainstream mode in manufacturing because of the higher flexibility and productivity compared with straight lines.
Honghao Zhang   +6 more
doaj   +1 more source

Flexural Behavior of 3D‐Printed Porous Bouligand‐Structured Polymers: Influence of Pitch Angle and Porosity

open access: yesAdvanced Engineering Materials, EarlyView.
This study examines how helicoidal architectures with different porosities respond to bending. Adjusting layer angle and spacing in 3D‐printed polymers reveals clear tradeoffs between stiffness, strength, and energy absorption. Experiments and simulations highlight designs that distribute stress effectively, offering pathways for optimizing lightweight
Praveenkumar Subhash Patil   +2 more
wiley   +1 more source

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