Results 101 to 110 of about 9,331,066 (286)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Technology Assessment in Business and Government [PDF]
, 1977 Hearings held by the Office of Technology Assessment (OTA) with the purpose of developing "a better understanding of how the processes of technology assessment have affected decisionmaking in the public and private sectors" (p.1)
United States. Congress. Office of Technology Assessment.
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FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Rolling out large scale assessment in a training environment
, 2012 This paper gives an account of a successful roll-out of a high stakes assessment. Although the target user group size wasn't significant at 10,000 users, the main challenge of the roll out was that it would be managed and delivered by a large number of ...
Steedman, Linda
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From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Human Resources for HealthBackground Quality assessments are being introduced in many countries to improve the quality of care and maintain acceptable quality levels. In South Korea, various quality assessments are being conducted to improve the quality of care, but there is ...
Seungju Kim +3 more
doaj +1 more source
Assessment 2007: Oil and Gas Activities in the Arctic - Effects and Potential Effects. Volume 1.
, 2010 This assessment report details the results of the 2007 Assessment of Oil and Gas Activities in the Arctic conducted under the auspices of the Arctic Council and coordinated by the Arctic Monitoring and Assessment Programme (AMAP)
Arctic Monitoring and Assessment Programme
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Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source