Results 41 to 50 of about 4,199,871 (247)

Investigating a new method for standardising essay marking using levels-based mark schemes

International Journal of Assessment Tools in Education, 2019
Standardisationis a procedure used by Awarding Organisations to maximise marking reliability,by teaching examiners to consistently judge scripts using a mark scheme.However, research shows that people are better at comparing two objects thanjudging each ...
Magda Werno, Karen Dunn, Tom Sutch, Jackie Greatorex, Jess Bowyer   +4 more
doaj   +1 more source

Adjunctive Therapeutic Plasma Exchange in Refractory Adult‐Onset Still's Disease Complicated by Secondary Macrophage Activation Syndrome: A Single‐Center Experience

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda, Tomohiro Saito, Masahide Mizobuchi, Tomoki Shimomura, Saki Kawamori, Mitsuru Kawanishi, Natsuko Hattori, Jo Sugiyama, Satoshi Tsubata, Hanami Horiguchi, Kazuki Abe, Nao Iida, Yuki Kajio, Nao Oguro, Ryo Yanai, Hirokazu Honda   +15 more
wiley   +1 more source

Report on Methodological Quality Assessment of Primary Care and General Practice Research in China in 2021: Qualitative and Mixed Methods Research Section [PDF]

Zhongguo quanke yixue
Background General practice has significant interdisciplinary characteristics, both qualitative research and mixed methods research are applicable to scientific research in this field.
Quality Assessment Group for Qualitative and Mixed Methods Research of Chinese General Practice
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Lipoedema research priorities: a Swedish priority-setting partnership for future treatment and diagnostic studies

BMJ Open
Objectives To identify research priorities related to the diagnosis, treatment and management of lipoedema.Design This was a research question priority-setting that ensured the involvement of patients, relatives and healthcare professionals in all parts.
Sara Fundell, Johan Dahlberg, Marie Österberg, Christel Hellberg, Jenny Stenman, Åsa G Andersson, Silvia Edling, Anders Liss   +7 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

What have we learnt about Mediterranean catchment hydrology? 30 years observing hydrological processes in the Vallcebre Research Catchments

Cuadernos de Investigación Geográfica, 2018
This paper presents the main results obtained from the study of hydrological processes in the Vallcebre Research Catchments since 1988. Distributed hydrometric measurements, environmental tracers and hydrological modelling were used to understand ...
P. Llorens, F. Gallart, C. Cayuela, M. Roig-Planasdemunt, E. Casellas, A.J. Molina, M. Moreno de las Heras, G. Bertran, E. Sánchez-Costa, J. Latron   +9 more
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source